Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727672 | 0.90 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL14894474 | 0.87 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL6114873 | 0.85 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2988331 | 0.85 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrogen Sulfide SCHEMBL27984120 | 0.85 | TSHR (0.81) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1972308 | 0.84 | ALDH1A1 (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5899198 | 0.84 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| Acetic Acid SCHEMBL27968233 | 0.83 | TSHR (0.78) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19066401 | 0.83 | TSHR (0.84) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11583525 | 0.83 | TSHR (0.84) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135150-B2 | Compositions and methods for improving the quality of chemically treated hair | L'OREAL (FR) | 2021-10-05 | — | — | US | disclosed |
| US-20180140532-A1 | COMPOSITIONS AND METHODS FOR RESTRUCTURING CHEMICALLY TREATED HAIR | L'OREAL (FR) | 2018-05-24 | — | — | US | disclosed |
| US-20180140531-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE QUALITY OF CHEMICALLY TREATED HAIR | L'OREAL (FR) | 2018-05-24 | — | — | US | disclosed |
| US-9186314-B2 | Compositions and methods for sealing the surface of keratinous substrates | L'OREAL (FR) | 2015-11-17 | — | — | US | disclosed |
| US-20130149274-A1 | COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES | L'OREAL S.A. (FR) | 2013-06-13 | — | — | US | disclosed |
| WO-2013061477-A1 | HAIR COLORATION BY THERMAL TRANSFER TECHNOLOGY | L'OREAL (FR) | 2013-05-02 | — | — | WO | disclosed |
| EP-1855643-B1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-1855638-B1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT ANTHRAQUINONE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | OREAL (FR) | 2011-06-22 | — | — | EP | disclosed |
| US-7722680-B2 | Dyeing of human keratin materials by dry thermal transfer of a direct dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-7651535-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct anthraquinone dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-26 | — | — | US | disclosed |
| US-7645304-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-12 | — | — | US | disclosed |
| US-20080168608-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Anthraquinone Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-07-17 | — | — | US | disclosed |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
| EP-1855636-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT AZOMETHINE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'OREAL (FR) | 2007-11-21 | — | — | EP | disclosed |
| US-20060242771-A1 | Anhydrous composition in the form of a film comprising a film-forming polymer and a direct dye, preparation and dyeing process using the composition | L'OREAL S.A. (FR) | 2006-11-02 | — | — | US | disclosed |
| US-20060230546-A1 | Anhydrous composition in the form of a film comprising at least one film-forming polymer and at least one oxidation dye, preparation, and dyeing process | L'OREAL S.A. (FR) | 2006-10-19 | — | — | US | disclosed |
| WO-2006089807-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT AZOMETHINE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'ORÉAL (FR) | 2006-08-31 | — | — | WO | disclosed |
| US-20020197225-A1 | Hair composition comprising a polysaccharide grafted with a polysiloxane, and a fixing polymer | L'OREAL S.A. (FR) | 2002-12-26 | — | — | US | disclosed |
| US-20020193265-A1 | Detergent cosmetic compositions containing an anionic surfactant derived from amino acids and salts thereof and a soluble conditioning agent and uses thereof | L'OREAL S.A. (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193265-A1 | Detergent cosmetic compositions containing an anionic surfactant derived from amino acids and salts thereof and a soluble conditioning agent and uses thereof | CUTA, SMURF1, SPAST | TSHR 3644/4885THRB 4035/4885POLB 2954/4885 |
| US-20020197225-A1 | Hair composition comprising a polysaccharide grafted with a polysiloxane, and a fixing polymer | ALG1, DPM1, SUCLG1 | TSHR 3631/4885THRB 3890/4885POLB 2856/4885 |
| US-20180140532-A1 | COMPOSITIONS AND METHODS FOR RESTRUCTURING CHEMICALLY TREATED HAIR | TET3, TYR, DDC | TSHR 3669/4885THRB 2481/4885POLB 259/4885 |
| US-20060242771-A1 | Anhydrous composition in the form of a film comprising a film-forming polymer and a direct dye, preparation and dyeing process using the composition | KRT18, DSG1, DSP | TSHR 4872/4885THRB 4684/4885POLB 2071/4885 |
| US-11135150-B2 | Compositions and methods for improving the quality of chemically treated hair | SRM, TET2, TET3 | TSHR 3406/4885THRB 2005/4885POLB 163/4885 |
| US-20080168608-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Anthraquinone Dye, Composition Comprising the Said Dye and Its Method of Preparation | KRT18, DSG1, KLK5 | TSHR 4226/4885THRB 4056/4885POLB 2144/4885 |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | KRT18, IK, KLK5 | TSHR 3805/4885THRB 3568/4885POLB 3591/4885 |
| US-20060230546-A1 | Anhydrous composition in the form of a film comprising at least one film-forming polymer and at least one oxidation dye, preparation, and dyeing process | KRT18, DSG1, DSP | TSHR 4877/4885THRB 4153/4885POLB 909/4885 |
| US-20130149274-A1 | COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES | KRT18, PLOD3, DDC | TSHR 4809/4885THRB 4430/4885POLB 396/4885 |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | KRT18, IK, DSG1 | TSHR 4059/4885THRB 3514/4885POLB 2910/4885 |
| US-20180140531-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE QUALITY OF CHEMICALLY TREATED HAIR | SRM, TET2, TET3 | TSHR 3406/4885THRB 2005/4885POLB 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.