SCHEMBL197307

SCHEMBL197307

CCOC(=O)c1cccc(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.61
CHRM2 P08172 1/20 0.58
CHRM4 P08173 1/20 0.58
CHRM1 P11229 1/20 0.58
CHRM3 P20309 1/20 0.58
ELANE P08246 1/20 0.58
CYP4F2 P78329 1/20 0.56
CYP4A11 Q02928 1/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
ALDH1A1 P00352 2/20 0.55
RAB9A P51151 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29443099 1.00 TRPV1 (0.61) TRPV1CHRM2CHRM4CHRM1CHRM3
Hydrochloric Acid SCHEMBL27624411 0.98 TRPV1 (0.59) TRPV1CHRM2CHRM4CHRM1CHRM3
Boric Acid SCHEMBL27780462 0.95 TRPV1 (0.57) TRPV1CHRM2CHRM4CHRM1CHRM3
SCHEMBL7471861 0.94 TRPV1 (0.56) TRPV1CHRM2CHRM4CHRM1CHRM3
SCHEMBL12812401 0.88 MAPT (0.60) TRPV1ELANECYP4F2CYP4A11LMNA
SCHEMBL110276 0.87 CYP4F2 (0.65) CYP4F2CYP4A11LMNAALDH1A1RAB9A
SCHEMBL6057368 0.86 LMNA (0.64) CHRM2CHRM4CHRM1CHRM3LMNA
SCHEMBL14335405 0.85 SMN1; SMN2 (0.61) TRPV1CHRM2CHRM4CHRM1CHRM3
SCHEMBL810821 0.85 L3MBTL1 (0.57) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL1567174 0.85 TRPV1 (0.51) TRPV1CHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113980117-B Fenpyroximate antigen and preparation method and application thereof 西南大学 2024-07-12 CN claimed
CN-117820460-A Methoxypiperidine ethyl antigen and preparation method and application thereof 西南大学 2024-04-05 CN claimed
CN-114560834-A Spirodiclofen hapten, antigen and antibody as well as preparation method and application thereof 西南大学 2022-05-31 CN claimed
CN-113980117-A Fenpyroximate antigen and preparation method and application thereof 西南大学 2022-01-28 CN claimed
CN-109694423-A Catalytic component for vinyl polymerization and preparation method thereof and catalyst for vinyl polymerization 中国石油化工股份有限公司 2019-04-30 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN claimed
US-12338241-B2 Bicyclic sulfones and sulfoxides and methods of use thereof GENENTECH, INC. (US) 2025-06-24 US disclosed
CN-111278809-B Bicyclic sulfones and sulfoxides, and methods of use thereof 豪夫迈·罗氏有限公司 2024-06-25 CN disclosed
EP-3704097-B1 BICYCLIC SULFONES AND SULFOXIDES AND METHODS OF USE THEREOF HOFFMANN LA ROCHE (CH) 2023-10-25 EP disclosed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 EP disclosed
US-20230242494-A1 MALONITRILE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2023-08-03 US disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
US-4910206-A Endotoxin induced lung injury SANDOZ PHARMACEUTICALS CORP. (US) 1990-03-20 US disclosed
EP-0015099-A1 Catalyst and process for producing olefin polymers or copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1980-09-03 EP disclosed
US-4088677-A CORROSION INHIBITORS, COMPLEXING AGENTS, FLAME RETARDANTS, PHARMACEUTICAL INTERMEDIATES HOECHST AKTIENGESELLSCHAFT (DT) 1978-05-09 US disclosed
US-3974243-A Carboxyphenyl-alkylphosphinic esters HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12338241-B2 Bicyclic sulfones and sulfoxides and methods of use thereof RB1, CCNE2, RPS3A TRPV1 4146/4885CHRM2 1920/4885CHRM4 3269/4885
US-20230242494-A1 MALONITRILE DERIVATIVES MAL2, ME1, C5 TRPV1 2594/4885CHRM2 129/4885CHRM4 584/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR TRPV1 2357/4885CHRM2 707/4885CHRM4 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.