Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732946 | 0.85 | LMNA (0.51) | LMNAALDH1A1PKMMMP9NPSR1 | |
| SCHEMBL19732918 | 0.84 | LMNA (0.59) | LMNAALDH1A1CA2 | |
| SCHEMBL19732921 | 0.81 | MEN1 (0.44) | LMNAALDH1A1HTTL3MBTL1CA2 | |
| SCHEMBL19732933 | 0.81 | L3MBTL1 (0.45) | LMNAALDH1A1NPSR1L3MBTL1F2 | |
| SCHEMBL19732922 | 0.80 | LMNA (0.45) | LMNAALDH1A1CA2MEN1KMT2A | |
| SCHEMBL19732963 | 0.80 | ALDH1A1 (0.51) | LMNAALDH1A1HTTF2PRSS1 | |
| SCHEMBL19732939 | 0.79 | TP53 (0.47) | LMNAALDH1A1L3MBTL1CA2MEN1 | |
| SCHEMBL19732930 | 0.77 | POLB (0.48) | LMNAALDH1A1HTTNPSR1ALOX12 | |
| SCHEMBL19732948 | 0.77 | HTT (0.55) | LMNAALDH1A1HTTL3MBTL1F2 | |
| SCHEMBL4256511 | 0.77 | LMNA (0.48) | LMNAALDH1A1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |