Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732939 | 0.93 | TP53 (0.47) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL19732918 | 0.92 | LMNA (0.59) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL19732963 | 0.90 | ALDH1A1 (0.51) | LMNAALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL19732931 | 0.89 | ACHE (0.46) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL19732917 | 0.89 | POLB (0.45) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL19732928 | 0.89 | RORC (0.44) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL19732921 | 0.86 | MEN1 (0.44) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL6242872 | 0.86 | CA1 (0.46) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL17291408 | 0.85 | PKM (0.50) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL19732934 | 0.85 | LMNA (0.48) | LMNAALDH1A1CA2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |