Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.97 |
| ▸ | MAPT | P10636 | 4/20 | 0.97 |
| ▸ | MEN1 | O00255 | 4/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.97 |
| ▸ | HTT | P42858 | 2/20 | 0.97 |
| ▸ | HPGD | P15428 | 2/20 | 0.97 |
| ▸ | RECQL | P46063 | 2/20 | 0.97 |
| ▸ | BLM | P54132 | 2/20 | 0.97 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.97 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.97 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.97 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorescein SCHEMBL29388667 | 0.98 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL30272223 | 0.98 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL3645090 | 0.98 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL16533 | 0.98 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL29371199 | 0.98 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL538249 | 0.97 | FTO (0.97) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL21410711 | 0.97 | FTO (0.97) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL3293893 | 0.97 | FTO (0.97) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL20503455 | 0.97 | FTO (0.97) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL21194999 | 0.97 | FTO (0.97) | FTOMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170122954-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) | 2017-05-04 | — | — | US | claimed |
| US-20150192564-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) | 2015-07-09 | — | — | US | claimed |
| EP-2335052-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | Enzo Life Sciences, Inc. (US) | 2011-06-22 | — | — | EP | claimed |
| WO-2010036922-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | ENZO LIFE SCIENCES, INC. (US) | 2010-04-01 | — | — | WO | claimed |
| US-20100081159-A1 | Profiling reactive oxygen, nitrogen and halogen species | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. | 2010-04-01 | — | — | US | claimed |
| US-20170122954-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) | 2017-05-04 | — | — | US | disclosed |
| US-9463437-B2 | Methods for scavenging nitric oxide using cerium oxide nanoparticles | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150192564-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20140227368-A1 | METHODS FOR SCAVENGING NITRIC OXIDE USING CERIUM OXIDE NANOPARTICLES | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140179014-A1 | FLUORESCENT NITRIC OXIDE PROBES AND ASSOCIATED METHODS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2014-06-26 | — | — | US | disclosed |
| US-8637323-B2 | Fluorescent nitric oxide probes and associated methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130302903-A1 | FLUORESCENT NITRIC OXIDE PROBES AND ASSOCIATED METHODS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2561338-A1 | FLUORESCENT NITRIC OXIDE PROBES AND ASSOCIATED METHODS | Board Of Regents, The University Of Texas System (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011133366-A1 | FLUORESCENT NITRIC OXIDE PROBES AND ASSOCIATED METHODS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-10-27 | — | — | WO | disclosed |
| EP-2335052-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | Enzo Life Sciences, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010036922-A1 | PROFILING REACTIVE OXYGEN, NITROGEN AND HALOGEN SPECIES | ENZO LIFE SCIENCES, INC. (US) | 2010-04-01 | — | — | WO | disclosed |
| US-20100081159-A1 | Profiling reactive oxygen, nitrogen and halogen species | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130302903-A1 | FLUORESCENT NITRIC OXIDE PROBES AND ASSOCIATED METHODS | NOS2, NOS3, NOS1 | FTO 1169/4885MAPT 4397/4885MEN1 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.