Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.45 |
| ▸ | RELA | Q04206 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10223594 | 0.84 | RAB9A (0.54) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL9224448 | 0.82 | RAB9A (0.53) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL23403728 | 0.79 | RAB9A (0.53) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL19733288 | 0.79 | LMNA (0.56) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL26654774 | 0.78 | RAB9A (0.45) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL23432611 | 0.78 | EGFR (0.38) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL31457686 | 0.78 | RAB9A (0.45) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL10222751 | 0.78 | RAB9A (0.49) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9105844 | 0.75 | NPC1 (0.61) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL903255 | 0.75 | NPC1 (0.61) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100465166-C | 5-Methyl-2-difluoromethyl benzoxazole and synthesis method thereof | UNIV SHANGHAI (CN) | 2009-03-04 | — | — | CN | claimed |
| CN-101012204-A | 5-Methyl-2-difluoromethyl benzoxazole and synthesis method thereof | UNIV SHANGHAI (CN) | 2007-08-08 | — | — | CN | claimed |
| EP-2817294-B1 | PROCESS FOR PRODUCTION OF DFMB DERIVATIVES | RHODIA OPERATIONS (FR) | 2017-12-27 | — | — | EP | disclosed |
| CN-100465166-C | 5-Methyl-2-difluoromethyl benzoxazole and synthesis method thereof | UNIV SHANGHAI (CN) | 2009-03-04 | — | — | CN | disclosed |
| CN-100465166-C | 5-Methyl-2-difluoromethyl benzoxazole and synthesis method thereof | UNIV SHANGHAI (CN) | 2009-03-04 | — | — | CN | disclosed |
| CN-101016276-A | 5-nitro-2-difluoromethylbenzimidazole and synthesis method thereof | UNIV SHANGHAI (CN) | 2007-08-15 | — | — | CN | disclosed |
| CN-101012204-A | 5-Methyl-2-difluoromethyl benzoxazole and synthesis method thereof | UNIV SHANGHAI (CN) | 2007-08-08 | — | — | CN | disclosed |
| CN-101012204-A | 5-Methyl-2-difluoromethyl benzoxazole and synthesis method thereof | UNIV SHANGHAI (CN) | 2007-08-08 | — | — | CN | disclosed |