Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973376 | 0.90 | ACHE (0.38) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL26189425 | 0.90 | MAOA (0.39) | ALDH1A1LMNATSHRMAPK1MAOA | |
| SCHEMBL26985642 | 0.80 | ALDH1A1 (0.37) | ALDH1A1LMNAMAOAMAOBSMN1; SMN2 | |
| SCHEMBL8467881 | 0.74 | LMNA (0.37) | ALDH1A1LMNATSHRACHETDP1 | |
| SCHEMBL1975999 | 0.72 | ACHE (0.42) | ALDH1A1MEN1KMT2ACYP3A4LMNA | |
| SCHEMBL19735872 | 0.72 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL19382447 | 0.72 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL808 | 0.71 | — | — | |
| SCHEMBL869949 | 0.69 | LMNA (0.39) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL10874516 | 0.69 | ACHE (0.38) | ALDH1A1MEN1KMT2AMAPK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092256-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-02 | — | — | WO | disclosed |