Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 3/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19735979 | 0.93 | ELANE (0.44) | STK17BKCNA3ELANEHTR2BCYP1A2 | |
| SCHEMBL19736020 | 0.92 | PRKCA (0.42) | KCNA3ELANEHTR2BCYP1A2CYP19A1 | |
| SCHEMBL19736106 | 0.88 | TTR (0.44) | CYP2A6STK17BALDH1A1KMT2AGLA | |
| SCHEMBL21543827 | 0.83 | CYP2A6 (0.48) | CYP2A6PDE5ASTK17BKCNA3ELANE | |
| SCHEMBL21543711 | 0.76 | CYP1A2 (0.49) | CYP2A6STK17BKCNA3ELANECYP1A2 | |
| SCHEMBL28050007 | 0.75 | KCNA3 (0.59) | CYP2A6PDE5AKCNA3ELANEHTR2A | |
| SCHEMBL21543826 | 0.75 | KCNA3 (0.46) | KCNA3ELANEHTR2BCYP1A2CYP19A1 | |
| SCHEMBL19735989 | 0.73 | KMT2A (0.45) | CYP1A2CYP2C19ALDH1A1KMT2AGLA | |
| SCHEMBL19735974 | 0.73 | CA1 (0.46) | CYP1A2CYP2C19ALDH1A1KMT2AGLA | |
| SCHEMBL11436177 | 0.70 | CYP1A2 (0.39) | CYP2A6PDE5AKCNA3ELANECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-06-01 | — | — | US | claimed |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-11-14 | — | — | US | claimed |
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-06-01 | — | — | US | disclosed |
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-06-01 | — | — | US | disclosed |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-11-14 | — | — | US | disclosed |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-11-14 | — | — | US | disclosed |
| WO-2017217741-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | 서울대학교 산학협력단 | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | TAS2R20, BLVRB, FDPS | CYP2A6 1971/4885PDE5A 12/4885STK17B 2306/4885 |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | TAS2R20, BLVRB, NOTUM | CYP2A6 1960/4885PDE5A 8/4885STK17B 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.