SCHEMBL1974403

SCHEMBL1974403

CC(C)(C)COC(=O)C1CC(=O)CN1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.36
ANPEP P15144 3/20 0.36
FKBP1A P62942 4/20 0.33
NR1D1 P20393 3/20 0.32
MAPT P10636 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
DPP4 P27487 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22654848 0.86 FKBP1A (0.37) FKBP1AMAPT
SCHEMBL27158695 0.86 FKBP1A (0.34) FKBP1AMAPTNFKB1NFKB2RELA
SCHEMBL2534501 0.84 NR1D1 (0.32) FKBP1ANR1D1
SCHEMBL27158567 0.82 FKBP1A (0.32) FKBP1ANR1D1
SCHEMBL201253 0.78 MMP2 (0.57) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL15083833 0.78 MMP2 (0.57) MMP2ANPEPDPP4DPP8DPP9
SCHEMBL27159103 0.77 FKBP1A (0.33) FKBP1A
SCHEMBL9273462 0.75 PTPN1 (0.41) MMP2ANPEPFKBP1ANR1D1MAPT
SCHEMBL8273056 0.75 PTPN1 (0.41) MMP2ANPEPFKBP1ANR1D1MAPT
SCHEMBL8404085 0.75 NR1D1 (0.42) MMP2ANPEPFKBP1ANR1D1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4332105-A1 PYRIDINO- OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2024-03-06 EP disclosed
US-8653070-B2 Hepatitis C virus inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2014-02-18 US disclosed
US-20110142798-A1 HEPATITIS C VIRUS INHIBITORS ENANTA PHARMACEUTICALS, INC. 2011-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110142798-A1 HEPATITIS C VIRUS INHIBITORS HAVCR2, SLC10A1, EIF2AK2 MMP2 2732/4885ANPEP 755/4885FKBP1A 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.