SCHEMBL19746633

SCHEMBL19746633

C=C(C)C(=O)N(C)CCN(CC)CC

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
MCHR1 Q99705 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22472138 0.88 PAOX (0.39) PAOX
SCHEMBL22472148 0.88 PAOX (0.39) PAOX
SCHEMBL9814628 0.87 TDP1 (0.36) CHRM1
SCHEMBL491530 0.83 PAOX (0.35) PAOXCHRM2CHRM4CHRM5CHRM1
SCHEMBL7729369 0.80 CA12 (0.33) PAOXCHRM2CHRM4CHRM5CHRM1
SCHEMBL375727 0.80 CA12 (0.34)
SCHEMBL22341 0.80
SCHEMBL8746116 0.78 TRPA1 (0.32)
Ammonia Solution, Strong SCHEMBL28079944 0.78 CA12 (0.33)
SCHEMBL9701553 0.78 MCHR1 (0.35) PAOXCHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200353090-A1 Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof Universite Paris-Saclay (FR) 2020-11-12 US claimed
EP-3710061-A1 POLYMER PRODRUGS AND SUBCUTANEOUS AND/OR INTRAMUSCULAR ADMINISTRATION THEREOF Centre National de la Recherche Scientifique (FR) 2020-09-23 EP claimed
CN-111615405-A Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof 国家科学研究中心 2020-09-01 CN claimed
US-12150996-B2 Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2024-11-26 US disclosed
CN-111615405-B Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof 国家科学研究中心 2023-11-28 CN disclosed
US-20200353090-A1 Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof Universite Paris-Saclay (FR) 2020-11-12 US disclosed
US-20200315967-A1 LIPID NANOPARTICLES MODERNATX, INC. (US) 2020-10-08 US disclosed
WO-2020196892-A1 RUBBER COMPOSITION AND METHOD FOR PRODUCING RUBBER COMPOSITION ZSエラストマー株式会社 2020-10-01 WO disclosed
EP-3710061-A1 POLYMER PRODRUGS AND SUBCUTANEOUS AND/OR INTRAMUSCULAR ADMINISTRATION THEREOF Centre National de la Recherche Scientifique (FR) 2020-09-23 EP disclosed
CN-111615405-A Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof 国家科学研究中心 2020-09-01 CN disclosed
WO-2017223135-A1 LIPID NANOPARTICLES MODERNATX, INC. (US) 2017-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12150996-B2 Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof IDE, SI, PYGM PAOX 967/4885CHRM2 2230/4885CHRM4 2490/4885
US-20200353090-A1 Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof IDE, SI, PYGM PAOX 972/4885CHRM2 2256/4885CHRM4 2519/4885
US-20200315967-A1 LIPID NANOPARTICLES EXOSC9, ABCB4, LIPA PAOX 341/4885CHRM2 4876/4885CHRM4 4734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.