SCHEMBL19749952

SCHEMBL19749952

c1ccc2c(c1)N=NC1CCCCC21

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 5/20 0.50
NOS3 P29474 3/20 0.46
NOS2 P35228 3/20 0.46
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PARP1 P09874 1/20 0.33
ALDH1A1 P00352 1/20 0.32
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453886 0.81 NOS1 (0.53) NOS1NOS3NOS2MEN1KMT2A
SCHEMBL3290310 0.67 MEN1 (0.56) NOS1NOS3NOS2MEN1KMT2A
SCHEMBL6643315 0.67 NOS1 (1.00) NOS1NOS3NOS2
SCHEMBL2515680 0.66 NOS1 (0.38) NOS1NOS3NOS2MEN1KMT2A
SCHEMBL7505121 0.65 NOS1 (0.52) NOS1NOS3NOS2MEN1KMT2A
SCHEMBL10293743 0.63 NOS3 (0.42) NOS1NOS3NOS2
SCHEMBL8309094 0.63 NOS3 (0.31) NOS1NOS3NOS2
SCHEMBL6644831 0.63 NOS1 (1.00) NOS1NOS3NOS2
SCHEMBL6599478 0.62 SIGMAR1 (0.43) MEN1KMT2AALDH1A1
Water SCHEMBL6608061 0.61 MAOA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9852896-B2 Method and apparatus for contained-electrospray for use in mass spectrometry and droplet reactions OHIO STATE INNOVATION FOUNDATION (US) 2017-12-26 US disclosed