Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293743 | 0.71 | NOS3 (0.42) | NOS3NOS1NOS2 | |
| Water SCHEMBL6608061 | 0.70 | MAOA (0.32) | — | |
| SCHEMBL17178589 | 0.68 | KDM1A (0.34) | — | |
| SCHEMBL17120918 | 0.67 | — | — | |
| SCHEMBL17253951 | 0.64 | KDM1A (0.37) | — | |
| SCHEMBL19749952 | 0.63 | NOS1 (0.50) | NOS3NOS1NOS2 | |
| SCHEMBL1203967 | 0.62 | CYP1A2 (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL13946085 | 0.62 | ALDH1A1 (0.38) | — | |
| Carbamic Acid SCHEMBL6382077 | 0.62 | NOS3 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL5487950 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888307-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034874-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1997-09-25 | — | — | WO | disclosed |