SCHEMBL1975182

SCHEMBL1975182

COc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@@H](O)C2C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 4/20 0.44
▸ SNCA P37840 3/20 0.44
▸ ALOX15 P16050 3/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ MMP2 P08253 4/20 0.43
▸ MMP9 P14780 4/20 0.43
▸ PRKD3 O94806 1/20 0.43
▸ PRKCG P05129 1/20 0.43
▸ PRKCB P05771 1/20 0.43
▸ PRKCA P17252 1/20 0.43
▸ PRKCH P24723 1/20 0.43
▸ PRKCI P41743 1/20 0.43
▸ PRKCE Q02156 1/20 0.43
▸ PRKCQ Q04759 1/20 0.43
▸ PRKCZ Q05513 1/20 0.43
▸ PRKCD Q05655 1/20 0.43
▸ PRKD1 Q15139 1/20 0.43
▸ XDH P47989 2/20 0.43
▸ PTGS1 P23219 2/20 0.42
▸ CYP19A1 P11511 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1973506 0.90 XDH (0.47) XDHCYP19A1ALDH1A1CYP3A4MAPK1
SCHEMBL6262441 0.87 HSD17B10 (0.56) HSD17B10SNCAALOX15CYP1A2MMP2
SCHEMBL6262437 0.87 HSD17B10 (0.56) HSD17B10SNCAALOX15CYP1A2MMP2
SCHEMBL2433863 0.87 HSD17B10 (0.56) HSD17B10SNCAALOX15CYP1A2MMP2
SCHEMBL14244672 0.79 SNCA (0.57) HSD17B10SNCAALOX15CYP1A2MMP2
SCHEMBL1430855 0.77 XDH (0.43) MMP2XDHCYP19A1ALDH1A1MEN1
SCHEMBL21122054 0.75 PRKD3 (0.71) HSD17B10SNCAALOX15CYP1A2MMP2
SCHEMBL12597042 0.75 SNCA (0.52) HSD17B10SNCAALOX15CYP1A2MMP2
SCHEMBL862094 0.75 KDM4E (0.74) HSD17B10SNCAALOX15PTGS1KDM4E
SCHEMBL13099975 0.75 KDM4E (0.74) HSD17B10SNCAALOX15PTGS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210015964-A1 METHOD OF FORMING AND USING A HEMOSTATIC HYDROCOLLOID UNITED HEALTH PRODUCTS INC (US) 2021-01-21 — — US disclosed
US-8557874-B2 Hemostatic material EPIC WOUND CARE, INC. (US) 2013-10-15 — — US disclosed
WO-2012142317-A1 FAST-CLOTTING WOUND DRESSINGS GAMMA THERAPEUTICS, INC (US) 2012-10-18 — — WO disclosed
EP-1803473-B1 Adhesive including medicament UNIV LOMA LINDA MED (US) 2011-06-22 — — EP disclosed
WO-2009070684-A2 HEMOSTATIC MATERIAL BAGGETT RICHARD W (US) 2009-06-04 — — WO disclosed
US-20090136562-A1 Hemostatic Material UNITED ECOENERGY CORP. 2009-05-28 — — US disclosed
WO-2009002768-A2 LIQUID BANDAGE MEDSPRING GROUP, INC. (US) 2008-12-31 — — WO disclosed
EP-1638491-A4 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT UNIV LOMA LINDA MED (US) 2008-05-28 — — EP disclosed
US-20080031929-A1 LIQUID BANDAGE MEDSPRING GROUP, INC. 2008-02-07 — — US disclosed
EP-1803473-A2 Adhesive including medicament Loma Linda University Medical Center (US) 2007-07-04 — — EP disclosed
US-20070026052-A1 Hemostatic material UNITED ECOENERGY CORP. 2007-02-01 — — US disclosed
EP-1638491-A2 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT Loma Linda University Medical Center (US) 2006-03-29 — — EP disclosed
US-20050123588-A1 Deployable multifunctional hemostatic agent LOMA LINDA UNIVERSITY MEDICAL CENTER 2005-06-09 — — US disclosed
WO-2005002510-A2 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT LOMA LINDA UNIVERSITY MEDICAL CENTER (US) 2005-01-13 — — WO disclosed
US-20030044380-A1 Adhesive including medicament LOMA LINDA UNIVERSITY 2003-03-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044380-A1 Adhesive including medicament ICAM1, VCAM1, EPCAM HSD17B10 4119/4885SNCA 3913/4885ALOX15 291/4885
US-20080031929-A1 LIQUID BANDAGE FGB, F2, F8 HSD17B10 1122/4885SNCA 3725/4885ALOX15 2374/4885
US-20050123588-A1 Deployable multifunctional hemostatic agent FGB, CHIT1, CHIA HSD17B10 4159/4885SNCA 3300/4885ALOX15 3159/4885
US-20070026052-A1 Hemostatic material F2, F8, F3 HSD17B10 2898/4885SNCA 3113/4885ALOX15 1864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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