Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973506 | 0.87 | XDH (0.47) | XDHALDH1A1CYP3A4MAPK1NR3C1 | |
| SCHEMBL1975182 | 0.77 | HSD17B10 (0.44) | XDHALDH1A1CYP3A4MAPK1CYP19A1 | |
| SCHEMBL15161369 | 0.75 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL15161417 | 0.75 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL3805652 | 0.74 | CYP3A4 (0.59) | CYP3A4MAPK1MMP2MMP14 | |
| SCHEMBL14244672 | 0.74 | SNCA (0.57) | XDHALDH1A1CYP3A4MAPK1MEN1 | |
| SCHEMBL25246785 | 0.73 | CYP3A4 (0.78) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL862416 | 0.73 | CYP3A4 (0.78) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL12597042 | 0.70 | SNCA (0.52) | XDHALDH1A1CYP3A4MAPK1MEN1 | |
| SCHEMBL862107 | 0.69 | MMP2 (0.59) | ALDH1A1CYP3A4MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300450-B1 | METHOD FOR THE PREPARATION OF C-4 COUPLED FLAVONOIDS, PROANTHOCYANIDINS AND ANALOGUES THEREOF | UNIV FREE STATE ZA (ZA) | 2015-12-23 | — | — | EP | claimed |
| US-8501970-B2 | Method for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2013-08-06 | — | — | US | claimed |
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2011-06-30 | — | — | US | claimed |
| EP-2300450-A1 | METHOD FOR THE PREPARATION OF C-4 COUPLED FLAVONOIDS, PROANTHOCYANIDINS AND ANALOGUES THEREOF | University Of The Free State (ZA) | 2011-03-30 | — | — | EP | claimed |
| WO-2009147645-A1 | METHOD FOR THE PREPARATION OF C-4 COUPLED FLAVONOIDS, PROANTHOCYANIDINS AND ANALOGUES THEREOF | UNIVERSITY OF THE FREE STATE (ZA) | 2009-12-10 | — | — | WO | claimed |
| EP-2300450-B1 | METHOD FOR THE PREPARATION OF C-4 COUPLED FLAVONOIDS, PROANTHOCYANIDINS AND ANALOGUES THEREOF | UNIV FREE STATE ZA (ZA) | 2015-12-23 | — | — | EP | disclosed |
| US-8501970-B2 | Method for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2013-08-06 | — | — | US | disclosed |
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2011-06-30 | — | — | US | disclosed |
| EP-2300450-A1 | METHOD FOR THE PREPARATION OF C-4 COUPLED FLAVONOIDS, PROANTHOCYANIDINS AND ANALOGUES THEREOF | University Of The Free State (ZA) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009147645-A1 | METHOD FOR THE PREPARATION OF C-4 COUPLED FLAVONOIDS, PROANTHOCYANIDINS AND ANALOGUES THEREOF | UNIVERSITY OF THE FREE STATE (ZA) | 2009-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | C9, PROC, MLN | XDH 3164/4885ALDH1A1 3071/4885CYP3A4 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.