Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.66 |
| ▸ | APP | P05067 | 4/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976131 | 1.00 | IAPP (0.66) | IAPPAPPALOX5IGF1RALOX15 | |
| SCHEMBL8392957 | 0.89 | IAPP (0.74) | IAPPAPPALOX5IGF1RALOX15 | |
| SCHEMBL8392954 | 0.89 | IAPP (0.74) | IAPPAPPALOX5IGF1RALOX15 | |
| SCHEMBL29489693 | 0.89 | IAPP (0.74) | IAPPAPPALOX5IGF1RALOX15 | |
| SCHEMBL29080020 | 0.85 | APP (0.85) | IAPPAPPALOX5CA12CA1 | |
| SCHEMBL14964001 | 0.84 | ALOX5 (0.67) | IAPPAPPALOX5ALOX15CA12 | |
| SCHEMBL29689081 | 0.84 | ALOX5 (0.67) | IAPPAPPALOX5ALOX15CA12 | |
| SCHEMBL29489701 | 0.83 | ALOX5 (0.65) | IAPPALOX5CA12CA4CA6 | |
| SCHEMBL13310702 | 0.81 | CA12 (0.53) | IAPPAPPALOX5ALOX15CA12 | |
| SCHEMBL8848008 | 0.81 | IAPP (0.67) | IAPPAPPALOX5CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072450-A1 | ANTIOXIDATIVE AND HEPATOPROTECTIVE COMPOSITIONS CONTAINING DIARYLHEPTANOIDS FROM ALNUS JAPONICA | RNL BIO CO., LTD. (KR) | 2013-03-21 | — | — | US | disclosed |
| US-20110144039-A1 | ANTIOXIDATIVE AND HEPATOPROTECTIVE COMPOSITIONS CONTAINING DIARYHEPTANOIDS FROM ALNUS JAPONICA | RNL BIO CO., LTD. (KR) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072450-A1 | ANTIOXIDATIVE AND HEPATOPROTECTIVE COMPOSITIONS CONTAINING DIARYLHEPTANOIDS FROM ALNUS JAPONICA | NR1H2, ALOX15B, ALOX12 | IAPP 821/4885APP 2556/4885ALOX5 96/4885 |
| US-20110144039-A1 | ANTIOXIDATIVE AND HEPATOPROTECTIVE COMPOSITIONS CONTAINING DIARYHEPTANOIDS FROM ALNUS JAPONICA | ALOX12, ALOX15B, ALOX15 | IAPP 910/4885APP 2305/4885ALOX5 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.