SCHEMBL19764665

SCHEMBL19764665

c1ccc(C2(c3ccc4c5ccccc5c5ccccc5c4c3)c3ccccc3Sc3ccccc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
OPRK1 P41145 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
CYP1A2 P05177 1/20 0.31
BCHE P06276 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
MAOA P21397 1/20 0.31
CNR1 P21554 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28267231 0.84 NOX1 (0.41) LMNAMEN1MAPTKMT2AKDM4E
SCHEMBL19764666 0.82 AHR (0.41) LMNAMEN1MAPTKMT2AKDM4E
SCHEMBL19764668 0.79 KDM4E (0.46) KDM4E
SCHEMBL23696826 0.77 LMNA (0.36) LMNAMEN1MAPTKMT2AKDM4E
SCHEMBL23697271 0.77 ACHE (0.44) LMNAMEN1KMT2AOPRK1ESR1
SCHEMBL19764699 0.77 LMNA (0.33) LMNAMEN1MAPTKMT2AKDM4E
SCHEMBL23697049 0.77 BCHE (0.37) LMNAMEN1MAPTKMT2AKDM4E
SCHEMBL16787339 0.75
SCHEMBL27267890 0.75 KDM4E (0.31) LMNAMEN1MAPTKMT2AKDM4E
SCHEMBL22169981 0.75 MAPT (0.38) LMNAMEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10566547-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-02-18 US disclosed
US-20180013074-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10566547-B2 Organic electroluminescent materials and devices PAX2, EYA2, NLRP1 LMNA 2691/4885MEN1 2810/4885MAPT 2328/4885
US-20180013074-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PAX2, EYA2, NLRP1 LMNA 2691/4885MEN1 2810/4885MAPT 2328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.