SCHEMBL28267231

SCHEMBL28267231

c1ccc(C2(c3ccccc3)c3ccccc3Sc3ccccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 5/20 0.41
MAPT P10636 4/20 0.41
BCHE P06276 4/20 0.41
GAA P10253 3/20 0.41
ACHE P22303 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAOA P21397 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CNR1 P21554 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
PTGS2 P35354 1/20 0.41
SNCA P37840 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23696826 0.88 LMNA (0.36) NOX1MAPTBCHEGAAACHE
SCHEMBL22169981 0.85 MAPT (0.38) NOX1MAPTBCHEGAAACHE
SCHEMBL20539744 0.85 NOX1 (0.48) NOX1MAPTBCHEGAAACHE
SCHEMBL21743573 0.84 OPRM1 (0.34) NOX1MAPTBCHEGAAACHE
SCHEMBL23697271 0.84 ACHE (0.44) NOX1BCHEACHEMEN1KMT2A
SCHEMBL16787352 0.84 OPRM1 (0.37) NOX1MAPTBCHEGAAACHE
SCHEMBL23697049 0.84 BCHE (0.37) NOX1MAPTBCHEGAAACHE
SCHEMBL21743587 0.84 MEN1 (0.38) NOX1MAPTBCHEGAAACHE
SCHEMBL21743559 0.84 MEN1 (0.35) NOX1MAPTBCHEGAAACHE
SCHEMBL19764665 0.84 LMNA (0.33) NOX1MAPTBCHEGAAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180665-A The conjugated compound of the thioxanthene of diphenyl containing 9,9- and preparation and application 华南理工大学 2019-01-11 CN claimed
CN-109476682-B Compound and organic light-emitting element comprising same 株式会社LG化学 2021-05-14 CN disclosed
CN-109476682-A Compound and organic light-emitting element comprising same 株式会社LG化学 2019-03-15 CN disclosed
CN-109180665-A The conjugated compound of the thioxanthene of diphenyl containing 9,9- and preparation and application 华南理工大学 2019-01-11 CN disclosed
CN-109180665-A The conjugated compound of the thioxanthene of diphenyl containing 9,9- and preparation and application 华南理工大学 2019-01-11 CN disclosed