Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.56 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524333 | 1.00 | HIF1A (0.74) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| Phenformin SCHEMBL136512 | 0.85 | LMNA (1.00) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| Phenformin SCHEMBL8425 | 0.85 | LMNA (1.00) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| Phenformin SCHEMBL10325620 | 0.85 | LMNA (1.00) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| Phenformin SCHEMBL787929 | 0.82 | LMNA (0.93) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| SCHEMBL23366564 | 0.79 | TSHR (0.69) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| [11C]Phenethylguanidine SCHEMBL837645 | 0.77 | HTR3A (0.80) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| SCHEMBL5839538 | 0.73 | HIF1A (0.65) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| Hydrochloric Acid SCHEMBL10876994 | 0.72 | HIF1A (0.62) | HIF1ATSHRLMNASLC22A2SLC22A1 | |
| SCHEMBL21966469 | 0.72 | ALDH1A1 (0.53) | HIF1ATSHRLMNASLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180015056-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING GROWTH OF CANCER STEM CELLS, CONTAINING ALDEHYDE INHIBITOR AND BIGUANIDE-BASED COMPOUND | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015056-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING GROWTH OF CANCER STEM CELLS, CONTAINING ALDEHYDE INHIBITOR AND BIGUANIDE-BASED COMPOUND | ALDH2, ALDH1A1, MKI67 | HIF1A 476/4885TSHR 4668/4885LMNA 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.