Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144974 | 0.81 | CES1 (0.52) | TSHRSRD5A2CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL28240782 | 0.80 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL8903743 | 0.79 | MAPT (0.55) | SRD5A2CA1CA2CA12CA3 | |
| SCHEMBL6737876 | 0.78 | ALDH1A1 (0.64) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21631867 | 0.78 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28203034 | 0.78 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10472299-B2 | Explosive microporous coordination polymers | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-11-12 | — | — | US | disclosed |
| US-20170369387-A1 | EXPLOSIVE MICROPOROUS COORDINATION POLYMERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-12-28 | — | — | US | disclosed |
| US-8454730-B2 | Method of operating gas storage and supply system | GM Global Technology Operations LLC (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2512640-A2 | METAL ORGANIC FRAMEWORK POLYMER MIXED MATRIX MEMBRANES | UOP LLC (US) | 2012-10-24 | — | — | EP | disclosed |
| US-20110252962-A1 | METHOD OF OPERATING GAS STORAGE AND SUPPLY SYSTEM | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2011081779-A2 | METAL ORGANIC FRAMEWORK POLYMER MIXED MATRIX MEMBRANES | UOP LLC (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20110138999-A1 | METAL ORGANIC FRAMEWORK POLYMER MIXED MATRIX MEMBRANES | UOP LLC (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472299-B2 | Explosive microporous coordination polymers | MCM5, NOX5, COX5A | TSHR 4629/4885TP53 2378/4885SRD5A2 4562/4885 |
| US-20170369387-A1 | EXPLOSIVE MICROPOROUS COORDINATION POLYMERS | MCM5, NOX5, COX5A | TSHR 4629/4885TP53 2378/4885SRD5A2 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.