Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781532 | 0.85 | ACP1 (0.46) | ACP1MAPTTP53GLAIDH1 | |
| SCHEMBL19781521 | 0.79 | GLA (0.42) | ACP1MAPTTP53SLC2A1GLA | |
| SCHEMBL20036833 | 0.77 | MAPT (0.41) | MAPTGLALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15213071 | 0.76 | P2RX3 (0.43) | ACP1MAPTTP53SLC2A1GLA | |
| SCHEMBL19781533 | 0.76 | MAPT (0.45) | ACP1MAPTTP53GLALMNA | |
| SCHEMBL5943059 | 0.76 | GLA (0.49) | MAPTTP53GLALMNASMN1; SMN2 | |
| SCHEMBL19781139 | 0.75 | ACP1 (0.41) | ACP1MAPTTP53NPC1SYK | |
| SCHEMBL19781255 | 0.74 | ALDH3A1 (0.46) | MAPTLMNAALDH1A1POLBHTT | |
| SCHEMBL15213069 | 0.71 | MAPT (0.54) | MAPTLMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2723103 | 0.70 | GLA (0.57) | MAPTTP53GLALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |