Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.38 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.36 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781532 | 0.86 | ACP1 (0.46) | ACP1TTBK1TTBK2NPC1TP53 | |
| SCHEMBL19781533 | 0.77 | MAPT (0.45) | ACP1NPC1TP53MAPTHDAC2 | |
| SCHEMBL19781791 | 0.75 | ACP1 (0.40) | ACP1TTBK1TTBK2NPC1TP53 | |
| SCHEMBL3025365 | 0.71 | MAOA (0.55) | MAOAMAOBPTGS2NPC1MAPT | |
| SCHEMBL21449914 | 0.69 | GRM1 (0.40) | PTGS2NPC1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19781509 | 0.69 | GABRP (0.52) | PTGS2CHRNB4CHRNA3CHRNA7CHRNA10 | |
| SCHEMBL19781262 | 0.67 | CHRNB4 (0.39) | PTGS2NPC1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19781774 | 0.67 | ACP1 (0.45) | ACP1TTBK1TTBK2NPC1TP53 | |
| SCHEMBL19781149 | 0.67 | ALDH2 (0.42) | MAOAMAOBPTGS2NPC1CHRNB4 | |
| SCHEMBL19781175 | 0.67 | PTGS2 (0.39) | MAOAPTGS2NPC1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |