Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782716 | 0.90 | CDC7 (0.39) | CDC7DBF4L3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL19782898 | 0.87 | ALDH1A1 (0.39) | CDC7DBF4L3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL19782724 | 0.84 | CDC7 (0.33) | CDC7DBF4L3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL19782384 | 0.76 | ALDH1A1 (0.38) | CDC7DBF4L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL19782899 | 0.74 | LMNA (0.42) | L3MBTL1HSD17B10ALDH1A1RAB9AMEN1 | |
| SCHEMBL19783110 | 0.73 | LMNA (0.35) | L3MBTL1HSD17B10ALDH1A1RAB9AMEN1 | |
| SCHEMBL19783004 | 0.72 | LMNA (0.34) | L3MBTL1HSD17B10ALDH1A1RAB9AMEN1 | |
| SCHEMBL19782395 | 0.69 | CDC7 (0.40) | CDC7DBF4ALDH1A1KDM4EMAPT | |
| SCHEMBL510314 | 0.63 | CDC7 (0.62) | CDC7DBF4HSD17B10ALDH1A1RAB9A | |
| SCHEMBL509072 | 0.63 | CDC7 (0.62) | CDC7DBF4HSD17B10ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |