Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782897 | 0.90 | CDC7 (0.38) | CDC7DBF4ALDH1A1RAB9AMEN1 | |
| SCHEMBL19782898 | 0.87 | ALDH1A1 (0.39) | CDC7DBF4ALDH1A1RAB9AMEN1 | |
| SCHEMBL19782724 | 0.84 | CDC7 (0.33) | CDC7DBF4ALDH1A1RAB9AMEN1 | |
| SCHEMBL19782384 | 0.74 | ALDH1A1 (0.38) | CDC7DBF4ALDH1A1RAB9AMEN1 | |
| SCHEMBL19783110 | 0.74 | LMNA (0.35) | ALDH1A1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL19783004 | 0.73 | LMNA (0.34) | ALDH1A1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL19782899 | 0.73 | LMNA (0.42) | ALDH1A1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL19782395 | 0.67 | CDC7 (0.40) | CDC7DBF4ALDH1A1KDM4EMAPT | |
| SCHEMBL510314 | 0.64 | CDC7 (0.62) | CDC7DBF4ALDH1A1RAB9AMEN1 | |
| SCHEMBL509072 | 0.64 | CDC7 (0.62) | CDC7DBF4ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | BARUCH S. BLUMBERG INSTITUTE | 2021-02-09 | — | — | US | disclosed |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE | 2019-08-08 | — | — | US | disclosed |
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | ABAT, AADAT, BCAT1 | CDC7 2682/4885DBF4 3687/4885ALDH1A1 571/4885 |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | ABAT, AADAT, BCAT1 | CDC7 2682/4885DBF4 3687/4885ALDH1A1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.