Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.34 |
| ▸ | LIMK2 | P53671 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782395 | 0.90 | CDC7 (0.40) | ALDH1A1CDC7DBF4KDM4EMAPT | |
| SCHEMBL19783003 | 0.87 | ADORA3 (0.41) | ALDH1A1KMT2AMEN1RAB9AKDM4E | |
| SCHEMBL21245761 | 0.85 | CDC7 (0.56) | ALDH1A1KMT2AMEN1RAB9ACDC7 | |
| SCHEMBL19782389 | 0.84 | DHODH (0.38) | ALDH1A1KMT2AMEN1HTTRAB9A | |
| SCHEMBL19782390 | 0.84 | DHODH (0.36) | ALDH1A1KMT2AMEN1HTTRAB9A | |
| SCHEMBL19782988 | 0.83 | CDC7 (0.46) | ALDH1A1KMT2AMEN1RAB9ACDC7 | |
| SCHEMBL19782897 | 0.76 | CDC7 (0.38) | ALDH1A1KMT2AMEN1HTTRAB9A | |
| SCHEMBL15993076 | 0.75 | NPC1 (0.48) | ALDH1A1KMT2AHTTRAB9AKDM4E | |
| SCHEMBL19782716 | 0.74 | CDC7 (0.39) | ALDH1A1KMT2AMEN1HTTRAB9A | |
| SCHEMBL19782394 | 0.74 | DHODH (0.38) | KMT2AMEN1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | BARUCH S. BLUMBERG INSTITUTE | 2021-02-09 | — | — | US | disclosed |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE | 2019-08-08 | — | — | US | disclosed |
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | ABAT, AADAT, BCAT1 | ALDH1A1 571/4885KMT2A 662/4885MEN1 2492/4885 |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | ABAT, AADAT, BCAT1 | ALDH1A1 571/4885KMT2A 662/4885MEN1 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.