Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 2/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21422259 | 0.87 | ESR2 (0.39) | TLR8ESR2GRM1CYP2A6CYP11B2 | |
| SCHEMBL19783854 | 0.87 | TLR8 (0.38) | TLR8ESR2GRM1CYP2A6CYP11B2 | |
| SCHEMBL19783976 | 0.86 | ADORA2A (0.39) | TLR8ESR2GRM1CYP2A6CYP11B2 | |
| SCHEMBL19783977 | 0.86 | ESR2 (0.41) | TLR8ESR2GRM1CYP2A6CYP11B2 | |
| SCHEMBL26684121 | 0.83 | TLR8 (0.41) | TLR8ESR2PTGS2GSRALOX12 | |
| SCHEMBL30667413 | 0.83 | TLR8 (0.41) | TLR8ESR2PTGS2GSRALOX12 | |
| SCHEMBL19783974 | 0.82 | POLB (0.38) | TLR8ESR2CYP2A6CYP11B2ADORA2A | |
| SCHEMBL19783867 | 0.82 | CYP11B2 (0.37) | TLR8ESR2GRM1CYP2A6CYP11B2 | |
| SCHEMBL19783973 | 0.81 | MAT2A (0.36) | TLR8ESR2CYP2A6CYP11B2ADORA2A | |
| SCHEMBL19783990 | 0.80 | TLR8 (0.44) | TLR8ESR2CYP2A6CYP11B2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-03 | — | — | US | disclosed |
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-03 | — | — | US | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | DDT, BCHE, ACHE | TLR8 3552/4885ESR2 3670/4885GRM1 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.