SCHEMBL1978447

SCHEMBL1978447

C=Cc1cc2c([nH]c3ccccc32)c2c1CC2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.45
AHR P35869 2/20 0.40
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
GPR3 P46089 1/20 0.39
PIM1 P11309 1/20 0.37
PIM3 Q86V86 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
KDM4E B2RXH2 1/20 0.37
AURKA O14965 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
RAB9A P51151 1/20 0.37
MAPK10 P53779 1/20 0.37
RIPK1 Q13546 1/20 0.37
PTK2B Q14289 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11315856 0.80 KIF11 (0.50) KIF11AHRMEN1MAPTKMT2A
SCHEMBL2641043 0.78 MAPT (0.42) KIF11AHRMEN1MAPTKMT2A
SCHEMBL3647710 0.76 MAPT (0.41) KIF11AHRMEN1MAPTKMT2A
SCHEMBL10794040 0.74 KIF11 (0.47) KIF11AHRMEN1MAPTKMT2A
SCHEMBL8124176 0.73 KMT2A (0.41) KIF11AHRMEN1MAPTKMT2A
SCHEMBL28320660 0.73 AHR (0.41) KIF11AHRMEN1MAPTKMT2A
SCHEMBL8128076 0.73 IDO1 (0.44) KIF11AHRMEN1MAPTKMT2A
SCHEMBL8123456 0.73 GABRP (0.43) KIF11AHRMEN1MAPTKMT2A
SCHEMBL8124644 0.73 ABCB1 (0.49) KIF11AHRMEN1MAPTKMT2A
Pavettine SCHEMBL36138 0.73 KIF11 (0.53) KIF11AHRMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2133572-B1 Centrifugal compressor for wet gas environments and method of manufacture GEN ELECTRIC (US) 2017-11-15 EP disclosed
US-8845281-B2 Centrifugal compressor for wet gas environments and method of manufacture GENERAL ELECTRIC COMPANY (US) 2014-09-30 US disclosed
US-20110142607-A1 CENTRIFUGAL COMPRESSOR FOR WET GAS ENVIRONMENTS AND METHOD OF MANUFACTURE NUOVO PIGNONE TECHNOLOGIE S.R.L. (IT) 2011-06-16 US disclosed
WO-2009152088-A1 CENTRIFUGAL COMPRESSOR FOR WET GAS ENVIRONMENTS AND METHOD OF MANUFACTURE GENERAL ELECTRIC COMPANY (US) 2009-12-17 WO disclosed
EP-2133572-A1 Centrifugal compressor for wet gas environments and method of manufacture General Electric Company (US) 2009-12-16 EP disclosed
US-7632466-B2 Ultraphobic surface structure having a plurality of hydrophilic areas QIAGEN GMBH (DE) 2009-12-15 US disclosed
US-7285331-B1 Ultraphobic surface QIAGEN GMBH (DE) 2007-10-23 US disclosed
US-6485836-B2 POLYURETHANE LAYER CONTAINING HOMOGENEOUSLY DISTRIBUTED PARTICLES COATED WITH A THERMOPLASTIC RESIN, DIRECTLY BONDED TO A SECOND LAYER THAT IS PREFERABLY A PREFABRICATED THERMOPLASTIC POLYMER BAYER AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
US-20020064659-A1 Polyurethane layer containing homogeneously distributed particles coated with a thermoplastic resin, directly bonded to a second layer that is preferably a prefabricated thermoplastic polymer BAYER AKTIENGESELLSCHAFT (DE) 2002-05-30 US disclosed