SCHEMBL2641043

SCHEMBL2641043

C=Cc1cc2c([nH]c3ccccc32)c(Br)c1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
AHR P35869 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GPR3 P46089 1/20 0.42
KIF11 P52732 7/20 0.40
PIM1 P11309 1/20 0.39
PIM3 Q86V86 1/20 0.39
PIM2 Q9P1W9 1/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11315856 0.83 KIF11 (0.50) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL8123456 0.82 GABRP (0.43) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL28761242 0.79 ALDH1A1 (0.48) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL3647710 0.79 MAPT (0.41) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL2641042 0.78 AHR (0.47) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL1978447 0.78 KIF11 (0.45) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL10794040 0.76 KIF11 (0.47) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL8124644 0.75 ABCB1 (0.49) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL8124176 0.75 KMT2A (0.41) MAPTAHRALDH1A1HSD17B10MEN1
SCHEMBL28320660 0.75 AHR (0.41) MAPTAHRALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4794015-B2 2011-10-12 JP claimed
US-7288296-B2 Multilayer optical compensator, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-10-30 US claimed
WO-2007001999-A1 MULTILAYERED OPTICAL COMPENSATOR NITTO DENKO CORPORATION (JP) 2007-01-04 WO claimed
US-20050286001-A1 Multilayer optical compensator, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-29 US claimed
EP-0350873-A2 Method for forming pattern and method for making semiconductor device HITACHI, LTD. (JP) 1990-01-17 EP disclosed
US-4109052-A LAMINATE FILM; COUPLING LAYER OF CROSSLINKED ACRYLIC POLYMER BOUND TO SUBSTRATE AND VAPORIZED METAL LAYERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-22 US disclosed