SCHEMBL197850

SCHEMBL197850

COc1cc(C=CC(=O)O)cc(O)c1O

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.87
PTGS1 P23219 2/20 0.87
PTGS2 P35354 2/20 0.87
KDM4E B2RXH2 7/20 0.74
GAA P10253 2/20 0.74
ALDH1A1 P00352 4/20 0.70
HSD17B10 Q99714 4/20 0.70
HPGD P15428 3/20 0.70
HTR1A P08908 1/20 0.70
HTR2C P28335 1/20 0.70
CA12 O43570 2/20 0.69
CA1 P00915 2/20 0.69
CA2 P00918 2/20 0.69
CA3 P07451 2/20 0.69
CA4 P22748 2/20 0.69
CA6 P23280 2/20 0.69
CA5A P35218 2/20 0.69
CA7 P43166 2/20 0.69
CA9 Q16790 2/20 0.69
CA14 Q9ULX7 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29537849 1.00 PKM (0.87) PKMPTGS1PTGS2KDM4EGAA
SCHEMBL10085810 1.00 PKM (0.87) PKMPTGS1PTGS2KDM4EGAA
Sinapinate SCHEMBL15515158 0.93 PKM (1.00) PKMPTGS1PTGS2KDM4EGAA
Sinapinate SCHEMBL37313 0.93 PKM (1.00) PKMPTGS1PTGS2KDM4EGAA
Sinapinate SCHEMBL37312 0.93 PKM (1.00) PKMPTGS1PTGS2KDM4EGAA
Sinapinate SCHEMBL27753908 0.93 PKM (1.00) PKMPTGS1PTGS2KDM4EGAA
Sinapinate SCHEMBL28937494 0.91 PKM (0.96) PKMPTGS1PTGS2KDM4EGAA
Caffeic Acid SCHEMBL7527406 0.91 KDM4E (0.76) PKMPTGS1PTGS2KDM4EGAA
SCHEMBL25308319 0.89 PKM (0.69) PKMPTGS1PTGS2KDM4EGAA
SCHEMBL22555964 0.89 ALOX5 (0.80) PKMPTGS1PTGS2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 730 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN claimed
EP-4601608-A1 ANTIPERSPIRANT COMPOSITIONS Elementis Specialties, Inc. (US) 2025-08-20 EP claimed
US-20250073143-A1 PERSONAL CARE COMPOSITIONS INCLUDING ANTIPERSPIRANT, DEODORANT, AND ASTRINGENT COMPOSITIONS ELEMENTIS SPECIALTIES INC (US) 2025-03-06 US claimed
CN-119317673-A Porous coating comprising minerals and oxygen scavengers for improving food shelf life OMYA国际股份公司 2025-01-14 CN claimed
CN-118924839-B Method for extracting and purifying allium mongolicum regel polyphenol with high biological activity 内蒙古大学 2025-01-10 CN claimed
US-20240398677-A1 ANTIPERSPIRANT COMPOSITIONS ELEMENTIS SPECIALTIES, INC. (US) 2024-12-05 US claimed
WO-2024249514-A1 ANTIPERSPIRANT COMPOSITIONS ELEMENTIS SPECIALTIES, INC. (US) 2024-12-05 WO claimed
US-12076316-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS INC. 2024-09-03 US claimed
EP-3645492-B1 PREPARATION PROCESS OF ORTHO ALKOXY BISPHENOL MONOMERS UNIV LEUVEN KATH (BE) 2024-08-21 EP claimed
CN-117554550-B Liquid chromatography tandem mass spectrometry detection method for catecholamine metabolites in plasma and combined stabilizer 大连博源医学科技有限公司 2024-06-04 CN claimed
CN-101448395-A Compositions and methods for increasing the value of plant products, enhancing their commercial quality, enhancing their resistance to external agents and increasing their polyphenol content ANTONI LESCHOT SANHUEZA ANDRES (CL) 2009-06-03 CN claimed
EP-2003968-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PRODUCTS, SO INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF Leschot Sanhueza, Andres Antonio (CL) 2008-12-24 EP claimed
US-20080166731-A1 Plant caffeic acid-3-O-methytransferase homologs CAHOON REBECCA E 2008-07-10 US claimed
US-20080166754-A1 Plant caffeic acid-3-O-methyltransferase homologs CAHOON REBECCA E 2008-07-10 US claimed
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof NAPPA ALVARO O 2007-10-04 US claimed
WO-2007110801-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF LESCHOT SANHUEZA ANDRES ANTONI (CL) 2007-10-04 WO claimed
US-20040014116-A1 Plant caffeic acid 3-0-methyltransferase homologs E.I. DU PONT DE NEMOURS AND COMPANY 2004-01-22 US claimed
US-20020026658-A1 Genes encoding sinapoylglucose: malate sinapoyltransferase and methods of use CHAPPLE CLINTON C S (US) 2002-02-28 US claimed
WO-2002004614-A2 GENES ENCODING SINAPOYLGLUCOSE: MALATE SINAPOYLTRANSFERASE AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2002-01-17 WO claimed
US-4241536-A Embryogenesis in vitro, induction of qualitative and quantitative changes in metabolites produced by plants and products thereof SAINT FIRMIN ANNETTE R 1980-12-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof C5, PNN, NQO1 PKM 2114/4885PTGS1 1945/4885PTGS2 1551/4885
US-12076316-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 PKM 2873/4885PTGS1 885/4885PTGS2 1209/4885
US-20240398677-A1 ANTIPERSPIRANT COMPOSITIONS FABP6, PON1, CYP2A6 PKM 3622/4885PTGS1 229/4885PTGS2 503/4885
US-20250073143-A1 PERSONAL CARE COMPOSITIONS INCLUDING ANTIPERSPIRANT, DEODORANT, AND ASTRINGENT COMPOSITIONS CUTA, DEK, PPARG PKM 3734/4885PTGS1 2287/4885PTGS2 3086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.