Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24107301 | 0.89 | CA2 (0.40) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL2199206 | 0.87 | CA2 (0.55) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL30978766 | 0.85 | CYP2A6 (0.45) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL17031795 | 0.84 | CA2 (0.36) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL29265219 | 0.83 | CYP2A6 (0.43) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL30703844 | 0.83 | ALDH1A1 (0.46) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL9257718 | 0.81 | P2RX7 (0.41) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL78891 | 0.80 | CA2 (0.48) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL24107260 | 0.79 | KIF11 (0.46) | CA2ALDH1A1KIF11PTPN5TRPA1 | |
| SCHEMBL9626847 | 0.78 | GABRA1 (0.56) | CA2GABRA1GABRB2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387941-A1 | Diphenyl-like Compound, Intermediate Thereof, Preparation Method Therefor, Pharmaceutical Composition Thereof And Uses Thereof | SHANGHAI MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2021-12-16 | — | — | US | disclosed |
| US-10246415-B2 | Process for preparing carbazoles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018013067-A1 | PROCESS FOR PREPARING CARBAZOLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DCLK2, DCLK1, PDCD2L | CA2 1213/4885GABRA1 467/4885GABRB2 293/4885 |
| US-20210387941-A1 | Diphenyl-like Compound, Intermediate Thereof, Preparation Method Therefor, Pharmaceutical Composition Thereof And Uses Thereof | CD274, PDCD1LG2, PDCD1 | CA2 4758/4885GABRA1 2221/4885GABRB2 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.