Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525687 | 0.80 | ALDH1A1 (0.39) | PAK1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL27658630 | 0.70 | ALDH1A1 (0.50) | PAK1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL20880132 | 0.70 | TERT (0.39) | ALDH1A1KDM4E | |
| SCHEMBL19793300 | 0.68 | KDM4E (0.34) | ALDH1A1KDM4E | |
| SCHEMBL22538976 | 0.66 | EPHX1 (0.40) | ALDH1A1RXFP1 | |
| SCHEMBL28991359 | 0.66 | ALDH1A1 (0.45) | PAK1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL20827763 | 0.66 | MPG (0.44) | ALDH1A1KDM4E | |
| SCHEMBL22538918 | 0.65 | FDPS (0.35) | ALDH1A1 | |
| SCHEMBL19780652 | 0.65 | NPC1 (0.38) | — | |
| SCHEMBL21274620 | 0.65 | ALDH1A1 (0.44) | PAK1ALDH1A1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180016257-A1 | Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016257-A1 | Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives | GCDH, HADH, OGDH | PAK1 4073/4885ALDH1A1 620/4885KDM4E 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.