Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881654 | 0.83 | HTR2C (0.35) | HTR2CLMNAHSD17B10ADRA2AADRA1A | |
| SCHEMBL1434579 | 0.81 | GRM4 (0.35) | HTR2CLMNAHSD17B10ADRA2AADRA1A | |
| SCHEMBL4742506 | 0.78 | DGKA (0.44) | HTR2CLMNAHSD17B10ADRA2AADRA1A | |
| SCHEMBL19387343 | 0.78 | HTR2C (0.36) | HTR2CLMNAHSD17B10 | |
| SCHEMBL18339269 | 0.76 | MMP1 (0.36) | — | |
| SCHEMBL4696007 | 0.76 | ALDH1A1 (0.44) | LMNAHSD17B10 | |
| SCHEMBL18823278 | 0.75 | HTR2C (0.41) | HTR2CLMNAHSD17B10ADRA2AADRA1A | |
| SCHEMBL22458075 | 0.75 | LMNA (0.31) | LMNAHSD17B10 | |
| SCHEMBL23408786 | 0.75 | HTR2C (0.34) | HTR2CLMNAHSD17B10 | |
| SCHEMBL3121478 | 0.74 | GLRA1 (0.39) | HTR2CLMNAHSD17B10ADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872918-B2 | Hydroxyl-polymer-drug-protein conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |