Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957789 | 0.79 | ABCB11 (0.33) | RAB9AARNPC1MEN1KMT2A | |
| SCHEMBL5228296 | 0.78 | AR (0.43) | EPHX2NR1H4RAB9AARNPC1 | |
| SCHEMBL26004753 | 0.78 | POLB (0.43) | ARMEN1KMT2ALMNATDP1 | |
| SCHEMBL18927848 | 0.77 | AR (0.44) | EPHX2NR1H4RAB9AARNPC1 | |
| SCHEMBL5482340 | 0.76 | RAB9A (0.40) | EPHX2NR1H4RAB9AARNPC1 | |
| SCHEMBL19327020 | 0.76 | ABCB11 (0.33) | RAB9AARNPC1MEN1KMT2A | |
| SCHEMBL144594 | 0.76 | ELANE (0.36) | RAB9AARNPC1MEN1KMT2A | |
| SCHEMBL7622862 | 0.75 | KDM4E (0.37) | RAB9AARNPC1MEN1KMT2A | |
| SCHEMBL8899200 | 0.74 | KDM4E (0.40) | RAB9AARNPC1MEN1KMT2A | |
| SCHEMBL12265865 | 0.73 | HTT (0.49) | ARMEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |