SCHEMBL144594

SCHEMBL144594

C=C(C)C(=O)OC(C)(C)Oc1ccc(C(C)(C)c2ccc(OC(C)(C)OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.36
KDM4E B2RXH2 6/20 0.35
POLB P06746 3/20 0.35
AR P10275 2/20 0.34
CYP3A4 P08684 2/20 0.34
ESR1 P03372 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
HTR6 P50406 1/20 0.34
ESRRG P62508 1/20 0.34
SLC6A3 Q01959 1/20 0.34
ESR2 Q92731 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 5/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
HTT P42858 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9181017 0.81 KDM4E (0.36) ELANEKDM4EPOLBARALDH1A1
SCHEMBL14173071 0.80 ELANE (0.56) ELANEKDM4EPOLBARCYP3A4
SCHEMBL30971 0.80 ELANE (0.56) ELANEKDM4EPOLBARCYP3A4
SCHEMBL18372587 0.79 ACACB (0.38) ELANEPOLBCYP3A4MAPTALDH1A1
SCHEMBL8957789 0.79 ABCB11 (0.33) ELANEKDM4EPOLBARCYP3A4
SCHEMBL19327020 0.79 ABCB11 (0.33) ELANEKDM4EPOLBARCYP3A4
SCHEMBL28256301 0.77 KDM4E (0.39) KDM4EPOLBARCYP3A4ESR1
SCHEMBL8899200 0.76 KDM4E (0.40) KDM4EPOLBARHPGDTSHR
SCHEMBL19789507 0.76 EPHX2 (0.38) KDM4EPOLBARMAPTALDH1A1
SCHEMBL3899570 0.75 ELANE (0.51) ELANEKDM4EPOLBARCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2623087-B1 Dental composite materials containing tricyclic plasticisers VOCO GMBH (DE) 2019-07-17 EP claimed
EP-2623086-B1 Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. VOCO GMBH (DE) 2019-07-10 EP claimed
US-9314408-B2 Dental composite materials comprising tricyclic plasticizers VOCO GMBH (DE) 2016-04-19 US claimed
US-20130203884-A1 DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS VOCO GMBH (DE) 2013-08-08 US claimed
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-20240180788-A1 PHOTOCATIONICALLY CURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2024-06-06 US disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
US-11958970-B2 Dental cut processing resin-based block TOKUYAMA DENTAL CORPORATION (JP) 2024-04-16 US disclosed
EP-4310128-A1 PHOTOCATIONICALLY CURABLE COMPOSITION Tokuyama Dental Corporation (JP) 2024-01-24 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-2548916-B2 ORGANIC/INORGANIC COMPOSITE FILLER AND MANUFACTURING METHOD THEREFOR TOKUYAMA DENTAL CORP (JP) 2023-03-22 EP disclosed
US-20030036582-A1 Dental curable composition TOKUYAMA CORPORATION (JP) 2003-02-20 US disclosed
EP-1236459-A1 PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2002-09-04 EP disclosed
EP-1226807-A1 DENTAL CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2002-07-31 EP disclosed
EP-0712622-B1 Dental composition and kit TOKUYAMA CORP (JP) 1999-09-01 EP disclosed
US-5925690-A UNSATURATED PHOSPHATE AND UNSATURATED POLYCARBOXYLIC ACID MONOMERS; BONDING AND TENSILE STRENGTH TO DENTIN AND ENAMEL TOKUYAMA CORPROATION (JP) 1999-07-20 US disclosed
US-5866631-A POLYMERIZABLE MONOMER CONTAINING AN ACIDIC GROUP, WATER, ARYL BORATE AND TRANSITION METAL COMPOUND. TOKUYAMA CORPORATION (JP) 1999-02-02 US disclosed
EP-0811368-A1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORPORATION (JP) 1997-12-10 EP disclosed
EP-0712622-A1 Dental composition and kit TOKUYAMA CORPORATION (JP) 1996-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240180788-A1 PHOTOCATIONICALLY CURABLE COMPOSITION CRY1, CRY2, TYR ELANE 4582/4885KDM4E 324/4885POLB 1278/4885
US-20130203884-A1 DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS CAD, PBRM1, PCBP1 ELANE 4105/4885KDM4E 2203/4885POLB 614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.