Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879675 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ADRA2AADRA2BADRA2CHSD17B10 | |
| SCHEMBL14088941 | 0.77 | ALDH1A1 (0.52) | ALDH1A1ADRA2AADRA2BADRA2CHSD17B10 | |
| SCHEMBL18676404 | 0.77 | GPR35 (0.56) | ALDH1A1ADRA2AADRA2BADRA2CHSD17B10 | |
| SCHEMBL3413676 | 0.71 | MAPT (0.54) | ALDH1A1HSD17B10HTTTLR2TLR1 | |
| SCHEMBL11291584 | 0.69 | ALDH1A1 (0.55) | ALDH1A1ADRA2AADRA2BADRA2CHSD17B10 | |
| SCHEMBL29739502 | 0.69 | ALDH1A1 (0.50) | ALDH1A1HSD17B10GPR35HTTKMT2A | |
| SCHEMBL14234731 | 0.69 | GPR35 (0.43) | ALDH1A1ADRA2AADRA2BADRA2CHSD17B10 | |
| SCHEMBL7711324 | 0.69 | ALDH1A1 (0.61) | ALDH1A1ADRA2AADRA2BADRA2CHSD17B10 | |
| SCHEMBL22025579 | 0.68 | MAPT (0.50) | ALDH1A1HSD17B10HTTTLR2TLR1 | |
| SCHEMBL7520916 | 0.67 | KMT2A (0.55) | ALDH1A1GPR35KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799431-B1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2018-01-24 | — | — | EP | disclosed |