Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18830891 | 0.69 | JAK2 (0.36) | JAK2NOS2 | |
| SCHEMBL15291319 | 0.68 | JAK2 (0.39) | JAK2NOS2BRD4 | |
| SCHEMBL3692774 | 0.65 | NOS2 (0.41) | JAK2NOS2 | |
| SCHEMBL3692772 | 0.65 | NOS2 (0.41) | JAK2NOS2 | |
| SCHEMBL30785015 | 0.65 | NOS2 (0.41) | JAK2NOS2 | |
| SCHEMBL5210885 | 0.63 | JAK2 (0.54) | JAK2NOS2BRD4CREBBP | |
| SCHEMBL28129799 | 0.62 | MAOB (0.43) | JAK2 | |
| SCHEMBL16426758 | 0.62 | RAB9A (0.55) | — | |
| SCHEMBL16426757 | 0.62 | RAB9A (0.55) | — | |
| SCHEMBL10871376 | 0.62 | JAK2 (0.33) | JAK2NOS2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492987-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | NIPPON STEEL & SUMIKIN CHEM CO (JP) | 2018-01-24 | — | — | EP | disclosed |