Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.44 |
| ▸ | LPL | P06858 | 7/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23075563 | 0.88 | LIPG (0.53) | DGAT1LIPGLPLENPP1ENPP3 | |
| SCHEMBL22639360 | 0.87 | LIPG (0.55) | DGAT1LIPGLPLENPP1ENPP3 | |
| SCHEMBL30866396 | 0.86 | LIPG (0.57) | DGAT1LIPGLPLENPP1ENPP3 | |
| SCHEMBL19794488 | 0.86 | DGAT1 (0.43) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL19106594 | 0.85 | LIPG (0.59) | DGAT1LIPGLPLALDH1A1MAPT | |
| SCHEMBL19794477 | 0.85 | LIPG (0.59) | DGAT1LIPGLPLALDH1A1MAPT | |
| SCHEMBL18015520 | 0.83 | DGAT1 (0.43) | DGAT1LIPGLPLKDM4EALDH1A1 | |
| SCHEMBL18015320 | 0.83 | LIPG (0.64) | DGAT1LIPGLPLKDM4EALDH1A1 | |
| SCHEMBL23964990 | 0.82 | LIPG (0.62) | DGAT1LIPGLPLENPP1ENPP3 | |
| SCHEMBL18015319 | 0.82 | LIPG (0.56) | DGAT1LIPGLPLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | DGAT1 1835/4885LIPG 4459/4885LPL 4682/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | DGAT1 1328/4885LIPG 3693/4885LPL 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.