SCHEMBL22639360

SCHEMBL22639360

CC1(C)OB(c2ccc(-c3ccc(-c4nc(-c5cccc6ccccc56)nc(-c5cccc6ccccc56)n4)cc3)cc2)OC1(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.55
LPL P06858 8/20 0.55
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.40
HPGD P15428 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAPK1 P28482 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23075563 0.99 LIPG (0.53) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL30866396 0.96 LIPG (0.57) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL23964990 0.92 LIPG (0.62) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL28906163 0.91 LIPG (0.57) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL19106608 0.88 LIPG (0.53) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL15197475 0.88 LIPG (0.63) LIPGLPLENPP3ENPP1P4HB
SCHEMBL19794483 0.87 DGAT1 (0.47) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL22639220 0.86 LIPG (0.62) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL28592940 0.86 LIPG (0.44) LIPGLPLKDM4EALDH1A1MAPT
SCHEMBL190941 0.86 LIPG (0.60) LIPGLPLENPP3ENPP1P4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220169659-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2022-06-02 US disclosed
WO-2021045469-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-03-11 WO disclosed
US-10833277-B2 Heterocyclic compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2020-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833277-B2 Heterocyclic compound and organic light emitting diode comprising same CRY1, CRY2, DDT LIPG 2767/4885LPL 1290/4885KDM4E 1307/4885
US-20220169659-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 LIPG 3582/4885LPL 2780/4885KDM4E 2673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.