Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979169 | 0.96 | FKBP1A (0.55) | FKBP1AF2PRSS1CTRB1CTSL | |
| SCHEMBL1980404 | 0.90 | HSD17B10 (0.53) | FKBP1AF2PRSS1MEN1KMT2A | |
| SCHEMBL13938196 | 0.90 | FKBP1A (0.49) | FKBP1AF2PRSS1CTRB1CTSL | |
| SCHEMBL1986802 | 0.88 | FKBP1A (0.48) | FKBP1AF2PRSS1CTSLCTSK | |
| SCHEMBL13938201 | 0.88 | FKBP1A (0.48) | FKBP1AF2PRSS1CTRB1CTSL | |
| SCHEMBL23565690 | 0.82 | FKBP1A (0.64) | FKBP1A | |
| SCHEMBL14130791 | 0.81 | CTRB1 (0.53) | FKBP1ACTRB1MEN1KMT2A | |
| SCHEMBL7228304 | 0.81 | FKBP1A (0.77) | FKBP1APIN1 | |
| SCHEMBL1978322 | 0.80 | FKBP1A (0.47) | FKBP1AF2CTRB1CTSLCTSK | |
| SCHEMBL7207593 | 0.79 | FKBP1A (0.48) | FKBP1AF2CTRB1CTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326834-B1 | 2-SUBSTITUTED HETEROCYCLIC COMPOUNDS | H LEE MOFFITT CANCER CT & RES (US) | 2011-06-29 | — | — | EP | disclosed |