Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | WNT3 | P56703 | 2/20 | 0.44 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980404 | 0.93 | HSD17B10 (0.53) | FKBP1AKMT2AMEN1HSD17B10UCHL1 | |
| SCHEMBL13938201 | 0.89 | FKBP1A (0.48) | FKBP1AKMT2AF2PRSS1KDM4E | |
| SCHEMBL13938199 | 0.88 | KDM4E (0.50) | KMT2AMEN1KDM4E | |
| SCHEMBL1979768 | 0.88 | FKBP1A (0.52) | FKBP1AKMT2AMEN1F2PRSS1 | |
| SCHEMBL1979225 | 0.88 | USP30 (0.50) | KMT2AMEN1KDM4E | |
| SCHEMBL1979169 | 0.88 | FKBP1A (0.55) | FKBP1AKMT2AMEN1F2PRSS1 | |
| SCHEMBL12597632 | 0.84 | KDM4E (0.52) | FKBP1AKMT2AKDM4E | |
| SCHEMBL13938196 | 0.83 | FKBP1A (0.49) | FKBP1AF2PRSS1CTSLCTSK | |
| SCHEMBL1979688 | 0.80 | STS (0.60) | KMT2AKDM4E | |
| SCHEMBL13938176 | 0.79 | STS (0.56) | KMT2ASFRP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326834-B1 | 2-SUBSTITUTED HETEROCYCLIC COMPOUNDS | H LEE MOFFITT CANCER CT & RES (US) | 2011-06-29 | — | — | EP | disclosed |