Dehydroabietic Acid

Dehydroabietic Acid

SCHEMBL678991

CC(C)c1ccc2c(c1)CCC1[C@](C)(C(=O)O)CCC[C@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KARS1 Q15046 5/20 1.00
▸ RXRA P19793 1/20 1.00
▸ CCNE1 P24864 1/20 1.00
▸ CDK2 P24941 1/20 1.00
▸ RXRB P28702 1/20 1.00
▸ RXRG P48443 1/20 1.00
▸ CYP3A4 P08684 4/20 0.81
▸ LMNA P02545 1/20 0.81
▸ POLB P06746 1/20 0.67
▸ APEX1 P27695 1/20 0.67
▸ PDE4D Q08499 1/20 0.67
▸ MEN1 O00255 3/20 0.64
▸ KMT2A Q03164 3/20 0.64
▸ CYP2D6 P10635 2/20 0.64
▸ CYP2C19 P33261 2/20 0.64
▸ TSHR P16473 2/20 0.64
▸ PDK1 Q15118 1/20 0.64
▸ PDK2 Q15119 1/20 0.64
▸ PDK3 Q15120 1/20 0.64
▸ PDK4 Q16654 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dehydroabietic Acid SCHEMBL222078 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL15313390 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL14653170 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL222079 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL18019015 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL2603437 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL15744753 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL20061641 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL19798161 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL9712221 1.00 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3075787-B1 PIGMENT DISPERSION AND PRODUCING METHOD THEREOF FUJIFILM CORP (JP) 2023-06-07 — — EP disclosed
US-11352317-B2 Rosin-based small molecular weight hydrogelator and its application JIANGNAN UNIVERSITY (CN) 2022-06-07 — — US disclosed
US-20210054249-A1 Hot Melt Adhesive Composition LG CHEM, LTD. (KR) 2021-02-25 — — US disclosed
US-20200239412-A1 NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING ELINDER FREDRIK (SE) 2020-07-30 — — US disclosed
US-20200223789-A1 Rosin-based small molecular weight hydrogelator and its application JIANGNAN UNIVERSITY (CN) 2020-07-16 — — US disclosed
WO-2020140326-A1 ROSIN-BASED SMALL MOLECULE HYDROGEL AGENT AND APPLICATION THEREOF 江南大学 2020-07-09 — — WO disclosed
US-10653173-B2 Method for masking unpleasant taste ANALYTICON DISCOVERY GMBH (DE) 2020-05-19 — — US disclosed
US-20190192413-A1 SKIN ANTI-AGING COMPOSITION CONTAINING DEHYDROGENATED ABIETIC ACID AND COMPOUND K AMOREPACIFIC CORP (KR) 2019-06-27 — — US disclosed
US-10280329-B2 Pigment dispersion and producing method thereof FUJIFILM CORPORATION (JP) 2019-05-07 — — US disclosed
US-20180193294-A1 Dehydroabietic acid (DHAA) derivatives for use as ion channel openers ELINDER FREDRIK (SE) 2018-07-12 — — US disclosed
US-20120322969-A1 DEHYDROABIETIC ACID POLYMER, COMPACT, METHOD FOR PRODUCING DEHYDROABIETIC ACID POLYMER, AND DEHYDROABIETIC ACID COMPOUND FUJIFILM CORPORATION (JP) 2012-12-20 — — US disclosed
US-20120322969-A1 DEHYDROABIETIC ACID POLYMER, COMPACT, METHOD FOR PRODUCING DEHYDROABIETIC ACID POLYMER, AND DEHYDROABIETIC ACID COMPOUND FUJIFILM CORPORATION (JP) 2012-12-20 — — US disclosed
US-20120101250-A1 NOVEL DEHYDROABIETIC ACID POLYMER FUJIFILM CORPORATION (JP) 2012-04-26 — — US disclosed
US-20120101250-A1 NOVEL DEHYDROABIETIC ACID POLYMER FUJIFILM CORPORATION (JP) 2012-04-26 — — US disclosed
US-8063127-B2 Antihazing agent for noncrystalline cycloolefin resins, resin compositions, and optical elements POLYPLASTICS CO., LTD. (JP) 2011-11-22 — — US disclosed
US-7533723-B2 Well bore treatment fluid SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2009-05-19 — — US disclosed
US-7533723-B2 Well bore treatment fluid SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2009-05-19 — — US disclosed
US-20090018236-A1 ANTIHAZING AGENT FOR NONCRYSTALLINE CYCLOOLEFIN RESINS, RESIN COMPOSITIONS, AND OPTICAL ELEMENTS POLYPLASTICS CO., LTD. (JP) 2009-01-15 — — US disclosed
US-20070095534-A1 Well bore treatment fluid SCHLUMBERGER TECHNOLOGY CORPORATION 2007-05-03 — — US disclosed
US-20070095534-A1 Well bore treatment fluid SCHLUMBERGER TECHNOLOGY CORPORATION 2007-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200223789-A1 Rosin-based small molecular weight hydrogelator and its application PADI6, CD44, DBN1 KARS1 3692/4885RXRA 1122/4885CCNE1 1378/4885
US-20180193294-A1 Dehydroabietic acid (DHAA) derivatives for use as ion channel openers KCNAB1, KCNA1, KCNE1 KARS1 1018/4885RXRA 1621/4885CCNE1 3997/4885
US-20120322969-A1 DEHYDROABIETIC ACID POLYMER, COMPACT, METHOD FOR PRODUCING DEHYDROABIETIC ACID POLYMER, AND DEHYDROABIETIC ACID COMPOUND DDOST, DHPS, DAD1 KARS1 1971/4885RXRA 823/4885CCNE1 2278/4885
US-20190192413-A1 SKIN ANTI-AGING COMPOSITION CONTAINING DEHYDROGENATED ABIETIC ACID AND COMPOUND K COL14A1, COL1A1, AK1 KARS1 1623/4885RXRA 809/4885CCNE1 321/4885
US-10653173-B2 Method for masking unpleasant taste MANBA, TAS1R1, BDKRB1 KARS1 3272/4885RXRA 1523/4885CCNE1 3050/4885
US-11352317-B2 Rosin-based small molecular weight hydrogelator and its application PADI6, CD44, DBN1 KARS1 3692/4885RXRA 1122/4885CCNE1 1378/4885
US-20200239412-A1 NEW DERIVATES OF DHAA WITH ELECTROSTATIC TUNING GRIN2B, ALOX15, GRIN2A KARS1 3065/4885RXRA 1372/4885CCNE1 2460/4885
US-20120101250-A1 NOVEL DEHYDROABIETIC ACID POLYMER DPAGT1, DDOST, ALAD KARS1 2615/4885RXRA 375/4885CCNE1 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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