Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341653 | 0.82 | HPGD (0.46) | CA12CA1CA2CA4CA7 | |
| SCHEMBL20515308 | 0.79 | — | — | |
| SCHEMBL20677619 | 0.78 | CYP1A2 (0.31) | — | |
| SCHEMBL19118530 | 0.76 | ALDH1A1 (0.42) | L3MBTL1MAPT | |
| SCHEMBL2464069 | 0.76 | MAPT (0.37) | HPGDMAPT | |
| SCHEMBL342299 | 0.75 | CA12 (0.54) | CA12CA1CA2CA4CA7 | |
| SCHEMBL14367054 | 0.75 | L3MBTL1 (0.41) | CA12CA1CA2CA4CA7 | |
| SCHEMBL28938345 | 0.74 | — | — | |
| SCHEMBL6972687 | 0.74 | CA12 (0.36) | CA12CA1CA2CA4CA7 | |
| SCHEMBL23581633 | 0.74 | CYP3A4 (0.30) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | claimed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | claimed |
| CN-109563371-A | Polysiloxane composition comprising having carried out the silanol group of acetal protection | 日产化学株式会社 | 2019-04-02 | — | — | CN | disclosed |
| CN-103781813-B | The epoxy resin adduct mixed | 蓝立方知识产权有限责任公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-101970400-B | Novel salt having fluorine-containing carbanion structure, derivative thereof, photoacid generator, resist material using the photoacid generator, and pattern forming method | CENTRAL GLASS CO LTD | 2015-04-22 | — | — | CN | disclosed |
| CN-101687740-B | Processes for production of 2-bromo-2,2-difluoroethanol and 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfonic acid salt | CENTRAL GLASS CO LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-101687741-B | 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfonic acid salt and method for producing the same | CENTRAL GLASS CO LTD | 2014-02-19 | — | — | CN | disclosed |
| CN-101982808-B | Chemically amplified resist composition and pattern forming process | SHINETSU CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |
| US-20130045948-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-02-21 | — | — | US | disclosed |
| CN-101625524-B | Photoresist composition and pattern forming method | SHINETSU CHEMICAL CO JP | 2012-11-28 | — | — | CN | disclosed |
| EP-2509978-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E.I. Du Pont De Nemours And Company (US) | 2012-10-17 | — | — | EP | disclosed |
| US-6887893-B1 | Methods and compositions for treatment and prevention of tumors, tumor-related disorders and cachexia | SANKYO COMPANY, LIMITED (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20050014814-A1 | Methods and compositions for the treatment and prevention of tumors, tumor-related disorders and cachexia | SANKYO COMPANY, LIMITED (JP) | 2005-01-20 | — | — | US | disclosed |
| US-20050004109-A1 | Methods and compositions for the treatment and prevention of tumors, tumor-related disorders and cachexia | SANKYO COMPANY, LIMITED | 2005-01-06 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | disclosed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| EP-0927555-A1 | Use of cyclooxygenase-2 inhibitors for the treatment and prevention of tumors, tumor-related disorders and cachexia | Sankyo Company Limited (JP) | 1999-07-07 | — | — | EP | disclosed |
| US-5908858-A | OSTEOPOROSIS; LEUKOTRIENE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1999-06-01 | — | — | US | disclosed |
| EP-0799823-A1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1997-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045948-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, NCEH1 | CA12 2358/4885CA1 839/4885CA2 926/4885 |
| US-20050014814-A1 | Methods and compositions for the treatment and prevention of tumors, tumor-related disorders and cachexia | CPT1B, PYGM, PTGES2 | CA12 806/4885CA1 981/4885CA2 520/4885 |
| US-20050004109-A1 | Methods and compositions for the treatment and prevention of tumors, tumor-related disorders and cachexia | CPT1B, PYGM, PTGES2 | CA12 806/4885CA1 981/4885CA2 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.