SCHEMBL19802189

SCHEMBL19802189

NCc1cccc2oc3ccccc3c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 5/20 0.43
HPGD P15428 4/20 0.43
MAPT P10636 3/20 0.43
MAOA P21397 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GLA P06280 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CYP3A4 P08684 1/20 0.43
PGAM1 P18669 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17196260 0.82 ALOX5 (0.58) ALOX5ALDH1A1KDM4EHPGDMAPT
SCHEMBL2954355 0.82 MAOA (0.47) ALOX5ALDH1A1KDM4EHPGDMAPT
SCHEMBL7035976 0.80 ALDH1A1 (0.43) ALOX5ALDH1A1KDM4EHPGDMAPT
SCHEMBL754169 0.80 ALDH1A1 (0.43) ALOX5ALDH1A1KDM4EHPGDMAPT
SCHEMBL13201404 0.80 ALDH1A1 (0.43) ALOX5ALDH1A1KDM4EHPGDMAPT
SCHEMBL9425618 0.80 MAOA (0.48) ALOX5ALDH1A1KDM4EHPGDMAPT
SCHEMBL24828780 0.77 ADRB2 (0.42) ALDH1A1KDM4EHPGDMAPTMAOA
SCHEMBL8521819 0.77 MAOA (0.41) ALDH1A1KDM4EHPGDMAPTMAOA
SCHEMBL15663291 0.77 KDM4E (0.59) ALOX5ALDH1A1KDM4EHPGDMAPT
SCHEMBL19772857 0.76 GABRA1 (0.46) ALDH1A1KDM4EHPGDMAPTMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018016742-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2018-01-25 WO disclosed