Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | PPARD | Q03181 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805922 | 0.86 | KDM1A (0.49) | ALDH1A1PPARGPPARDPPARALMNA | |
| SCHEMBL12613855 | 0.82 | ALDH1A1 (0.56) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL1486251 | 0.82 | ALDH1A1 (0.60) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL19437107 | 0.79 | CA2 (0.61) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL9781244 | 0.79 | ALDH1A1 (0.62) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL1599701 | 0.79 | KDM4E (0.69) | ALDH1A1CA2POLBKDM4EGAA | |
| SCHEMBL29484286 | 0.79 | KDM4E (0.69) | ALDH1A1CA2POLBKDM4EGAA | |
| SCHEMBL1034882 | 0.77 | CA2 (0.69) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL31114400 | 0.77 | CA2 (0.69) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL20456229 | 0.76 | ALDH1A1 (0.70) | ALDH1A1POLBTDP1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| US-20210309647-A1 | Apoptosis Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-10-07 | — | — | US | disclosed |
| US-11034680-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-06-15 | — | — | US | disclosed |
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| US-20190152960-A1 | Apoptosis Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2019-05-23 | — | — | US | disclosed |
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152960-A1 | Apoptosis Inhibitors | BAX, SDHA, SDHB | ALDH1A1 550/4885PPARG 976/4885PPARD 1225/4885 |
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | ALDH1A1 550/4885PPARG 976/4885PPARD 1225/4885 |
| US-11034680-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | ALDH1A1 550/4885PPARG 976/4885PPARD 1225/4885 |
| US-20210309647-A1 | Apoptosis Inhibitors | BAX, SDHA, SDHB | ALDH1A1 550/4885PPARG 976/4885PPARD 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.