Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805900 | 0.86 | ALDH1A1 (0.61) | ALDH1A1PPARGPPARDPPARALMNA | |
| SCHEMBL3306706 | 0.83 | KDM1A (0.49) | KDM1AMAOAMAOBDBHALDH1A1 | |
| SCHEMBL23046575 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOBDBHALDH1A1 | |
| SCHEMBL296365 | 0.81 | HTR7 (0.58) | KDM1AMAOAMAOBDBHCYP17A1 | |
| SCHEMBL19806072 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPK1HTTTUBB1 | |
| SCHEMBL12890690 | 0.79 | DBH (0.51) | KDM1AMAOAMAOBDBHALDH1A1 | |
| SCHEMBL8481621 | 0.79 | ALDH1A1 (0.71) | ALDH1A1PPARGPPARDPPARALMNA | |
| SCHEMBL21534766 | 0.78 | HTR1A (0.51) | KDM1AMAOAMAOBDBHPPARD | |
| SCHEMBL9135638 | 0.77 | CYP17A1 (0.49) | KDM1AMAOAMAOBDBHALDH1A1 | |
| SCHEMBL16355197 | 0.77 | KDM1A (0.49) | KDM1AMAOAMAOBDBHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309647-A1 | Apoptosis Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-10-07 | — | — | US | disclosed |
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309647-A1 | Apoptosis Inhibitors | BAX, SDHA, SDHB | KDM1A 1294/4885MAOA 2052/4885MAOB 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.