SCHEMBL1980627

SCHEMBL1980627

COC(=O)C(=O)/C=C1\COC(C)(C)O1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1980630 1.00 KDM4E (0.33) KDM4EALDH1A1MAPT
SCHEMBL6413133 0.77
SCHEMBL25268081 0.75
SCHEMBL1980929 0.72 MAPT (0.31) ALDH1A1MAPT
SCHEMBL1979303 0.72
SCHEMBL1980109 0.70 APOBEC3A (0.36) KDM4EALDH1A1MAPT
SCHEMBL1980110 0.70 APOBEC3A (0.36) KDM4EALDH1A1MAPT
SCHEMBL6078917 0.70
SCHEMBL516164 0.69
SCHEMBL1980023 0.63 ALDH1A1 (0.37) KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222435-B2 Dioxolane and dioxane derivatives and a process for their preparation BAYER CROPSCIENCE AG (DE) 2012-07-17 US claimed
US-12612377-B2 Process for preparing aminofuranes BAYER AKTIENGESELLSCHAFT (DE) 2026-04-28 US disclosed
US-20240010626-A1 METHOD FOR PRODUCING CARBONYLAMINOFURANS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-11 US disclosed
US-20230339876-A1 PROCESS FOR PREPARING AMINOFURANES BAYER AKTIENGESELLSCHAFT (DE) 2023-10-26 US disclosed
US-8586753-B2 Process for the preparation of 1-alkyl and 1-aryl-5-pyrazolecarboxylic acid derivatives BAYER CROPSCIENCE AG (DE) 2013-11-19 US disclosed
EP-2513063-B1 Method for manufacturing 1-alkyl-/1-aryl-5-pyrazolcarbonic acid derivatives BAYER CROPSCIENCE AG (DE) 2013-11-06 EP disclosed
EP-2513063-A1 METHOD FOR PRODUCING 1-ALKYL-/1-ARYL-5-PYRAZOLE-CARBOXYLIC ACID DERIVATIVES Bayer CropScience AG (DE) 2012-10-24 EP disclosed
US-8222435-B2 Dioxolane and dioxane derivatives and a process for their preparation BAYER CROPSCIENCE AG (DE) 2012-07-17 US disclosed
US-20110152532-A1 Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2011-06-23 US disclosed
US-20110152531-A1 Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation BAYER CROPSCIENCE AG (DE) 2011-06-23 US disclosed
WO-2011073101-A1 METHOD FOR PRODUCING 1-ALKYL-/1-ARYL-5-PYRAZOLE-CARBOXYLIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-06-23 WO disclosed
WO-2011073100-A1 NOVEL DIOXOLANE AND DIOXANE DERIVATIVES, AND A METHOD FOR THE PRODUCTION THEREOF BAYER CROPSCIENCE AG (DE) 2011-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010626-A1 METHOD FOR PRODUCING CARBONYLAMINOFURANS CYP2F1, DHFR, CYP4F2 KDM4E 2482/4885ALDH1A1 113/4885MAPT 1925/4885
US-20110152532-A1 Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives AADAC, CYP4X1, CYP4Z1 KDM4E 1594/4885ALDH1A1 317/4885MAPT 4646/4885
US-20230339876-A1 PROCESS FOR PREPARING AMINOFURANES GFPT1, CYP4F11, CYP4F2 KDM4E 1027/4885ALDH1A1 774/4885MAPT 2783/4885
US-20110152531-A1 Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation ACOX1, CYP4X1, ANTXR2 KDM4E 982/4885ALDH1A1 401/4885MAPT 4745/4885
US-12612377-B2 Process for preparing aminofuranes CCRL2, CCR3, TOP1 KDM4E 2500/4885ALDH1A1 1076/4885MAPT 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.