Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16340432 | 0.86 | CYP3A4 (0.37) | CYP3A4CYP2C19PPARGPPARAHTT | |
| SCHEMBL17293858 | 0.85 | HPGD (0.33) | PPARGPPARAHTTMAPTSMN1; SMN2 | |
| SCHEMBL16340401 | 0.84 | HPGD (0.33) | L3MBTL1PPARGPPARAHTTMAPT | |
| SCHEMBL19275156 | 0.78 | — | — | |
| SCHEMBL5996915 | 0.78 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1POLBCYP3A4CYP2C19 | |
| SCHEMBL5994480 | 0.77 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1POLBCYP3A4CYP2C19 | |
| SCHEMBL21252638 | 0.76 | NFE2L2 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL13075826 | 0.73 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1POLBCYP3A4CYP2C19 | |
| SCHEMBL5835530 | 0.72 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1POLBCYP3A4CYP2C19 | |
| SCHEMBL341388 | 0.71 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406394-B | Process for the preparation of substituted phenylisoxazoline derivatives | 拜耳作物科学股份公司 | 2021-09-03 | — | — | CN | disclosed |
| US-10604495-B2 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-31 | — | — | US | disclosed |
| US-10604495-B2 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-31 | — | — | US | disclosed |
| EP-3265446-B1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-14 | — | — | EP | disclosed |
| EP-3265446-B1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-14 | — | — | EP | disclosed |
| US-10189799-B2 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | disclosed |
| US-10189799-B2 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20190016691-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-17 | — | — | US | disclosed |
| US-20190016691-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-17 | — | — | US | disclosed |
| US-20180030002-A1 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20180030002-A1 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20180030002-A1 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189799-B2 | Process for preparing substituted phenylisoxazoline derivatives | CYP3A7, CYP3A4, CYP4X1 | ALDH1A1 1036/4885L3MBTL1 4856/4885POLB 1028/4885 |
| US-10604495-B2 | Process for preparing substituted phenylisoxazoline derivatives | CYP3A7, CYP3A4, CYP4X1 | ALDH1A1 1036/4885L3MBTL1 4856/4885POLB 1028/4885 |
| US-20190016691-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLISOXAZOLINE DERIVATIVES | CYP3A7, CYP3A4, CYP4X1 | ALDH1A1 1036/4885L3MBTL1 4856/4885POLB 1028/4885 |
| US-20180030002-A1 | Process for preparing substituted phenylisoxazoline derivatives | CYP3A7, CYP3A4, CYP4X1 | ALDH1A1 1036/4885L3MBTL1 4856/4885POLB 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.