Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20454598 | 0.65 | — | — | |
| SCHEMBL8388914 | 0.64 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL9800255 | 0.63 | PARL (0.41) | — | |
| SCHEMBL1665112 | 0.62 | — | — | |
| SCHEMBL22339447 | 0.62 | P2RX7 (0.43) | — | |
| SCHEMBL19439807 | 0.61 | PTPN1 (0.58) | PTPN1 | |
| SCHEMBL13064334 | 0.61 | — | — | |
| SCHEMBL18465887 | 0.60 | BRD4 (0.32) | — | |
| SCHEMBL2039024 | 0.59 | — | — | |
| SCHEMBL12360461 | 0.58 | BRD4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030059-A1 | COELENTERAZINE ANALOGUES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030059-A1 | COELENTERAZINE ANALOGUES | GLB1, SI, TCF7L2 | PTPN1 4800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.