Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143378 | 0.81 | ALDH1A1 (0.62) | ALDH1A1P2RX7TDP1 | |
| SCHEMBL4038474 | 0.78 | HPGD (0.69) | HPGDCNR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL27454018 | 0.77 | ACLY (0.59) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5099387 | 0.73 | CNR1 (0.48) | HPGDCNR1ALDH1A1P2RX7MEN1 | |
| SCHEMBL1808181 | 0.73 | IDO1 (0.57) | CNR1ACLY | |
| SCHEMBL3529974 | 0.73 | HPGD (0.67) | HPGDCNR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6337215 | 0.73 | GPR84 (0.48) | HPGDCNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9083835 | 0.73 | ACLY (0.51) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL4778926 | 0.73 | ACLY (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4ACLY | |
| SCHEMBL7934893 | 0.72 | P2RX7 (0.53) | CNR1ALDH1A1P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2337778-A1 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT | Absolute Science, INC. (US) | 2011-06-29 | — | — | EP | disclosed |
| EP-2190293-A1 | COMPOUNDS AND METHODS FOR TREATING ZINC MATRIX METALLOPROTEASE DEPENDENT DISEASES | Absolute Science, INC. (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2010033360-A1 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT | 1/3 ABSOLUTE SCIENCE, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2009045761-A1 | COMPOUNDS AND METHODS FOR TREATING ZINC MATRIX METALLOPROTEASE DEPENDENT DISEASES | ABSOLUTE SCIENCE, INC. (US) | 2009-04-09 | — | — | WO | disclosed |