Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16016397 | 0.79 | HTR6 (0.39) | HTR6HTR2CHTR2BTDP1MAPK1 | |
| SCHEMBL8203524 | 0.70 | ALDH1A1 (0.41) | HTR6HTR2CHTR2BTDP1MAPK1 | |
| SCHEMBL1020748 | 0.68 | HTR6 (0.36) | HTR6HTR2CHTR2BTDP1MAPK1 | |
| SCHEMBL19289192 | 0.67 | RIPK1 (0.40) | TDP1TAAR1LMNAHPGD | |
| SCHEMBL1020357 | 0.67 | SMN1; SMN2 (0.39) | HTR6HTR2CHTR2BTDP1MAPK1 | |
| SCHEMBL16018751 | 0.66 | HTR6 (0.38) | HTR6HTR2CHTR2BTDP1MAPK1 | |
| SCHEMBL13718831 | 0.63 | TAAR1 (0.45) | HTR6HTR2CTAAR1ALDH1A1 | |
| SCHEMBL13718765 | 0.63 | NPC1 (0.40) | HTR6HTR2CTDP1MAPK1TAAR1 | |
| SCHEMBL19832429 | 0.62 | HTR6 (0.38) | HTR6HTR2CHTR2BTDP1MAPK1 | |
| SCHEMBL1020888 | 0.62 | TAAR1 (0.44) | HTR6HTR2CTDP1MAPK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119782-B1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | REMYND NV (BE) | 2018-01-31 | — | — | EP | disclosed |