Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 3/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.52 |
| ▸ | FBP1 | P09467 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038102 | 0.86 | KMT2A (0.55) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL30895880 | 0.83 | CTSD (0.52) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL19840432 | 0.83 | CTSD (0.52) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL24438715 | 0.83 | CTSD (0.60) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL8736939 | 0.80 | CTSD (0.52) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL24118868 | 0.78 | KMT2A (0.57) | MAPTKMT2AMEN1CTSDHSPD1 | |
| SCHEMBL11823166 | 0.77 | FBP1 (0.65) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL31038148 | 0.77 | ALDH1A1 (0.54) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL31038144 | 0.76 | ALDH1A1 (0.58) | MAPTKMT2AMEN1KDM4EJAK2 | |
| SCHEMBL8363011 | 0.76 | FBP1 (0.58) | MAPTKMT2AMEN1KDM4EJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884046-B1 | Method of treating lung cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-02-06 | — | — | US | disclosed |